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@cheny19 cheny19 released this 09 Jun 04:48
· 134 commits to master since this release
v2.6.0
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Learn about vigilant mode.

In this release, there's a key update in the simulation stage. NanoSim is capable of simulating fastq files now! We characterized a few datasets and used truncated log-normal distribution models to simulate the base quality of unaligned reads, matched bases, erroneous bases for genome and transcriptome reads separately.

Most of the changes in this release are for the simulation stage.

Other features:

  1. Perfect reads can have poly(A) tails now.

  2. Read files and error profiles for unaligned reads are separated from aligned reads now.

Bug fixes:

  1. Minor bugs in IR modeling, eliminated the exon extraction biases and read orientation problem

  2. Reversed the strandness information in simulation, which was opposite to the real orientation

  3. Solved occasional crashes when simulating unaligned reads

  4. Fixed the reversed head/tail length for reads from negative strand in transcriptome simulaiton

  5. Added missing file in pre-trained model

Assets 3
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