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[ENH] Add the possibility to use ANTsPy instead of ANTs for `T1Li…
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…near` and `FlairLinear` (#1244)

* add antspy to dependencies

* try replacing n4biasfieldcorrection

* implement the use-antspy option for t1-linear and flair-linear

* update documentation
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NicolasGensollen authored Aug 2, 2024
1 parent cb479ec commit c8c64e0
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Showing 11 changed files with 742 additions and 97 deletions.
31 changes: 19 additions & 12 deletions clinica/pipelines/engine.py
Original file line number Diff line number Diff line change
Expand Up @@ -381,6 +381,7 @@ def __init__(
base_dir: Optional[str] = None,
parameters: Optional[dict] = None,
name: Optional[str] = None,
ignore_dependencies: Optional[List[str]] = None,
):
"""Init a Pipeline object.
Expand All @@ -407,6 +408,10 @@ def __init__(
name : str, optional
Pipeline name. Defaults to None.
ignore_dependencies : List of str
List of names of dependencies whose installation checking procedure should be ignored.
Defaults to None (i.e. all dependencies will be checked).
Raises
------
RuntimeError: [description]
Expand Down Expand Up @@ -446,6 +451,7 @@ def __init__(

self._name = name or self.__class__.__name__
self._parameters = parameters or {}
self._ignore_dependencies = ignore_dependencies or []

if not self._bids_directory:
if not self._caps_directory:
Expand Down Expand Up @@ -768,18 +774,19 @@ def _check_dependencies(self):
if not self.info:
self._load_info()
for d in self.info["dependencies"]:
if d["type"] == "software":
check_software(d["name"])
elif d["type"] == "binary":
check_binary(d["name"])
elif d["type"] == "toolbox":
pass
elif d["type"] == "pipeline":
pass
else:
raise Exception(
f"Pipeline.check_dependencies() Unknown dependency type: '{d['type']}'."
)
if d["name"] not in self._ignore_dependencies:
if d["type"] == "software":
check_software(d["name"])
elif d["type"] == "binary":
check_binary(d["name"])
elif d["type"] == "toolbox":
pass
elif d["type"] == "pipeline":
pass
else:
raise Exception(
f"Pipeline.check_dependencies() Unknown dependency type: '{d['type']}'."
)
self._check_custom_dependencies()

return self
Expand Down
105 changes: 94 additions & 11 deletions clinica/pipelines/t1_linear/anat_linear_pipeline.py
Original file line number Diff line number Diff line change
@@ -1,7 +1,7 @@
# Use hash instead of parameters for iterables folder names
# Otherwise path will be too long and generate OSError
from pathlib import Path
from typing import List
from typing import List, Optional

from nipype import config

Expand All @@ -24,6 +24,44 @@ class AnatLinear(Pipeline):
A clinica pipeline object containing the AnatLinear pipeline.
"""

def __init__(
self,
bids_directory: Optional[str] = None,
caps_directory: Optional[str] = None,
tsv_file: Optional[str] = None,
overwrite_caps: Optional[bool] = False,
base_dir: Optional[str] = None,
parameters: Optional[dict] = None,
name: Optional[str] = None,
ignore_dependencies: Optional[List[str]] = None,
use_antspy: bool = False,
):
from clinica.utils.stream import cprint

super().__init__(
bids_directory=bids_directory,
caps_directory=caps_directory,
tsv_file=tsv_file,
overwrite_caps=overwrite_caps,
base_dir=base_dir,
parameters=parameters,
ignore_dependencies=ignore_dependencies,
name=name,
)
self.use_antspy = use_antspy
if self.use_antspy:
self._ignore_dependencies.append("ants")
cprint(
(
"The AnatLinear pipeline has been configured to use ANTsPy instead of ANTs.\n"
"This means that no installation of ANTs is required, but the antspyx Python "
"package must be installed in your environment.\nThis functionality has been "
"introduced in Clinica 0.9.0 and is considered experimental.\n"
"Please report any issue or unexpected results to the Clinica developer team."
),
lvl="warning",
)

@staticmethod
def get_processed_images(
caps_directory: Path, subjects: List[str], sessions: List[str]
Expand Down Expand Up @@ -215,6 +253,10 @@ def _build_core_nodes(self):
import nipype.pipeline.engine as npe
from nipype.interfaces import ants

from clinica.pipelines.t1_linear.tasks import (
run_ants_registration_task,
run_n4biasfieldcorrection_task,
)
from clinica.pipelines.tasks import crop_nifti_task, get_filename_no_ext_task

from .anat_linear_utils import print_end_pipeline
Expand All @@ -228,30 +270,61 @@ def _build_core_nodes(self):
name="ImageID",
)

# The core (processing) nodes
# =====================================

# 1. N4biascorrection by ANTS. It uses nipype interface.
n4biascorrection = npe.Node(
name="n4biascorrection",
interface=ants.N4BiasFieldCorrection(dimension=3, save_bias=True),
interface=(
nutil.Function(
function=run_n4biasfieldcorrection_task,
input_names=[
"input_image",
"bspline_fitting_distance",
"output_prefix",
"output_dir",
"save_bias",
"verbose",
],
output_names=["output_image"],
)
if self.use_antspy
else ants.N4BiasFieldCorrection(dimension=3)
),
)

n4biascorrection.inputs.save_bias = True
if self.use_antspy:
n4biascorrection.inputs.output_dir = str(self.base_dir)
n4biascorrection.inputs.verbose = True
if self.name == "t1-linear":
n4biascorrection.inputs.bspline_fitting_distance = 600
else:
n4biascorrection.inputs.bspline_fitting_distance = 100

# 2. `RegistrationSynQuick` by *ANTS*. It uses nipype interface.
ants_registration_node = npe.Node(
name="antsRegistrationSynQuick", interface=ants.RegistrationSynQuick()
name="antsRegistrationSynQuick",
interface=(
nutil.Function(
function=run_ants_registration_task,
input_names=[
"fixed_image",
"moving_image",
"random_seed",
"output_prefix",
"output_dir",
],
output_names=["warped_image", "out_matrix"],
)
if self.use_antspy
else ants.RegistrationSynQuick()
),
)
ants_registration_node.inputs.fixed_image = self.ref_template
ants_registration_node.inputs.transform_type = "a"
ants_registration_node.inputs.dimension = 3
if not self.use_antspy:
ants_registration_node.inputs.transform_type = "a"
ants_registration_node.inputs.dimension = 3

if random_seed := self.parameters.get("random_seed", None):
ants_registration_node.inputs.random_seed = random_seed
random_seed = self.parameters.get("random_seed", None)
ants_registration_node.inputs.random_seed = random_seed or 0

# 3. Crop image (using nifti). It uses custom interface, from utils file

Expand Down Expand Up @@ -301,6 +374,16 @@ def _build_core_nodes(self):
(self.input_node, print_end_message, [("anat", "anat")]),
]
)
if self.use_antspy:
self.connect(
[
(
image_id_node,
n4biascorrection,
[("image_id", "output_prefix")],
),
]
)
if not (self.parameters.get("uncropped_image")):
self.connect(
[
Expand Down
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