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Update mutation_extractor:
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- Simplified the logic of the `is_dissimilar_loci` if statement. Additionally, changed the threshold for determining a mutation in Consensus from 75% to 50% (to accommodate the insertion allele in Cas3 Tyr Barcode10).
- Updated `detect_anomalies` to use MLPClassifier to detect mutations more flexibly and accurately compared to the previous threshold setting with MiniBatchKMeans.
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akikuno committed Jul 8, 2024
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15 changes: 14 additions & 1 deletion docs/RELEASE.md
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# Current Release

## v0.5.2 (2024-XX-XX)
# v0.5.2 (2024-XX-XX)

## 📝 Documentation

+ Add `FAQ.md` and `FAQ_JP.md` to provide answers to questions. [[Commit Detail](https://github.com/akikuno/DAJIN2/commit/1172fddd34c382f92b6778d6f30fd733b458cc04)]

## 🌟 New Features

- Update `mutation_extractor` [[Commit Detail](https://github.com/akikuno/DAJIN2/commit/9444ee701ee52adeb6271552eff70667fb49b854)]
- Simplified the logic of the `is_dissimilar_loci` if statement. Additionally, changed the threshold for determining a mutation in Consensus from 75% to 50% (to accommodate the insertion allele in Cas3 Tyr Barcode10).
- Updated `detect_anomalies` to use MLPClassifier to detect mutations more flexibly and accurately compared to the previous threshold setting with MiniBatchKMeans.

## 🔧 Maintenance

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+ Resolve the B023 Function definition does not bind loop variable `alignment_lengths` issue. [[Commit Detail](https://github.com/akikuno/DAJIN2/commit/9c85d2f0410494a9b71d9905fad2f9e4efe30ed7)]

+ Add `question.yml` in GitHub Issue template. [[Commit Detail](https://github.com/akikuno/DAJIN2/commit/1172fddd34c382f92b6778d6f30fd733b458cc04)]


## 🐛 Bug Fixes

+ Update `cssplits_handler._get_index_of_large_deletions`: Modified to split large deletions when a match of 10 or more bases is found within the identified large deletion. Issue: #42 [[Commit Detail](https://github.com/akikuno/DAJIN2/commit/xxxxx)]
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