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Remove implausible mitochondrial LDH reaction #642

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Remove implausible mitochondrial LDH reaction #642

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Devlin-Moyer
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@Devlin-Moyer Devlin-Moyer commented Jun 14, 2023

Main improvements in this PR:

#528 proposed fixes to GPRs that were implemented in #540, but #528 also proposed removing MAR04280 (see #528 for justification), and since that's a relatively minor change to make and that issue's been open for a while, I figured I might as well open a PR to take care of it, so this PR removes MAR04280.

I hereby confirm that I have:

  • Tested my code on my own computer for running the model
  • Selected develop as a target branch
  • Any removed reactions and metabolites have been moved to the corresponding deprecated identifier lists

@edkerk
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edkerk commented Jun 27, 2023

In #528, removal of MAR04280 (= mitochondrial LDH) was proposed based on a detailed review on mitochondrial lactate shuttle, which seems convincing to me, but I'm not sure consensus was reached.

@haowang-bioinfo
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close for now, feel free to reopen

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3 participants