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Update multi-disease serology data #1165

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Update multi-disease serology data #1165

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Update multi-disease serology data
senthil10 Aug 5, 2024
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Update the right table
senthil10 Aug 6, 2024
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add missing info
senthil10 Aug 6, 2024
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255 changes: 177 additions & 78 deletions content/english/dashboards/multidisease_serology.md
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toc: true
---

<div class="alert alert-info">All data last updated: 2024-08-05</div>

## Introduction

The COVID-19 pandemic highlighted the importance of serological surveillance in tracking viral transmission dynamics, understanding immune responses, guiding vaccination strategies, and assisting in decisions related to public health. High-throughput serological assays for SARS-CoV-2 were developed very early in the pandemic at KTH and SciLifeLab to enable surveillance of populations globally. For information about work done with SARS-CoV-2 during the pandemic, see the [historical background section](#historical-background).
Expand Down Expand Up @@ -376,153 +378,250 @@ The multi-disease serological assay is under constant development and will gradu
<table id="antigens" class="table table-hover" width="100%">
<thead class="table-light">
<tr>
<th scope="col">Group</th>
<th scope="col">Subtype/Linage/Strain</th>
<th scope="col">Virus Type</th>
<th scope="col">Variant</th>
<th scope="col">Protein</th>
<th scope="col">Details</th>
<th scope="col">Host</th>
</tr>
</thead>
<tr>
<td>Pertussis</td>
<td>Bordetella pertussis Filamentous Hemagglutinin (FHA)</td>
</tr>
<tr>
<td>Pertussis</td>
<td>Bordetella pertussis Filamentous Hemagglutinin (FHA) - Bulk antigen</td>
</tr>
<tr>
<td>Pertussis</td>
<td>B. Pertussis toxin (mutant)</td>
<td>Bordetella Pertussis</td>
<td></td>
<td>Filamentous haemagglutinin</td>
<td></td>
<td></td>
</tr>
<tr>
<td>Pertussis</td>
<td>B. Pertussis Pertactin Protein [His]</td>
<td>Bordetella Pertussis</td>
<td></td>
<td>Pertussis toxin</td>
<td>Native</td>
<td></td>
</tr>
<tr>
<td>Pertussis</td>
<td>Bordetella pertussis Filamentous Hemagglutinin (FHA) - Nativeantigen</td>
<td>Bordetella Pertussis</td>
<td></td>
<td>Membrane protein Pertactin</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Pertussis</td>
<td>B. Pertussis whole-cell (strain tahoma I)</td>
<td>Bordetella Pertussis</td>
<td>Strain Tomaha I</td>
<td>Filamentous haemagglutinin</td>
<td>Native</td>
<td></td>
</tr>
<tr>
<td>Measles</td>
<td>Measles Virus Nucleoprotein (HEK293)</td>
<td>Bordetella Pertussis</td>
<td>Strain Tomaha I</td>
<td>Native protein, whole cell</td>
<td></td>
<td></td>
</tr>
<tr>
<td>Measles</td>
<td>Native Measles virus</td>
<td>Clostridium Tetanis</td>
<td></td>
<td>Tetanus toxin</td>
<td>Heavy chain fragment C</td>
<td></td>
</tr>
<tr>
<td>Rotavirus</td>
<td>Rotavirus VP7 Protein</td>
<td>Clostridium Tetanis</td>
<td></td>
<td>Tetanus toxoid</td>
<td>Native</td>
<td></td>
</tr>
<tr>
<td>Rotavirus</td>
<td>RotaVirus (Strain SA-11)</td>
<td>Corynebacterium Diphteria</td>
<td></td>
<td>Diphtheria toxin</td>
<td>Mutated G52E, native full length</td>
<td></td>
</tr>
<tr>
<td>Rubella</td>
<td>Rubella virus nucleoprotein, C-terminal His-tag</td>
<td>Corynebacterium Diphteria</td>
<td>Strain NCTC 10648</td>
<td></td>
<td></td>
<td></td>
</tr>
<tr>
<td>Rubella</td>
<td>Rubella Virus Grade 4, natural antigen.</td>
<td>Cytomegalovirus</td>
<td></td>
<td>Glycoprotein B</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Rubella</td>
<td>Rubella E1</td>
<td>Epstein Barr Virus</td>
<td></td>
<td>Glycoprotein 125</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Rubella</td>
<td>Rubella virus E1, C-terminal SHFC-tag</td>
<td>Hepatitis Virus</td>
<td>HBV</td>
<td></td>
<td>Surface antigen, subtype adw</td>
<td>P. pastoris</td>
</tr>
<tr>
<td>Rubella</td>
<td>Rubella Spike Ectodomain (E1-E2)</td>
<td>Human Papillomavirus (HPV)</td>
<td>Type 16</td>
<td>Capsid protein L1</td>
<td>Full length</td>
<td>Yeast</td>
</tr>
<tr>
<td>Diphtheria</td>
<td>Diphtheria mutated toxin</td>
<td>Human Papillomavirus (HPV)</td>
<td>Type 18</td>
<td>Capsid protein L1</td>
<td>Full length</td>
<td>S. cerevisae</td>
</tr>
<tr>
<td>Diphtheria</td>
<td>Diphtheria Toxoid</td>
<td>Human Papillomavirus (HPV)</td>
<td>Type 6</td>
<td>Capsid protein L1</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Mumps</td>
<td>Mumps Virus Nucleoprotein Recombinant</td>
<td>Human Papillomavirus (HPV)</td>
<td>Type 33</td>
<td>Capsid protein L1</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Mumps</td>
<td>Mumps virus nucleoprotein</td>
<td>Measles Virus</td>
<td></td>
<td>Nucleoprotein</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Mumps</td>
<td>Mumps virus nucleoprotein, inactivated pathogen.</td>
<td>Measles Virus</td>
<td>Strain Edmonston</td>
<td></td>
<td>Native</td>
<td>Vero cells</td>
</tr>
<tr>
<td>Mumps</td>
<td>Native Mumps virus</td>
<td>Mumps Virus</td>
<td></td>
<td>Nucleoprotein</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Humant Papillomvirus</td>
<td>HPV type 16 L1 Protein (full length)</td>
<td>Mumps Virus</td>
<td>Strain Jeryl-Lynn</td>
<td>Nucleoprotein</td>
<td>Full length</td>
<td>HEK</td>
</tr>
<tr>
<td>Humant Papillomvirus</td>
<td>HPV type 18 L1 Protein (full length)</td>
<td>Mumps Virus</td>
<td></td>
<td>Nucleoprotein</td>
<td></td>
<td></td>
</tr>
<tr>
<td>Humant Papillomvirus</td>
<td>Recombinant HPV type 6 L1 protein (VLP)</td>
<td>Mumps Virus</td>
<td>Strain Enders</td>
<td></td>
<td>Native</td>
<td>BSC-1 cells</td>
</tr>
<tr>
<td>Humant Papillomvirus</td>
<td>Recombinant Human Papilloma Virus type 33 L1 protein (VLP)</td>
<td>Poliovirus</td>
<td>Type 1, Strain Sabin</td>
<td>Capsid protein</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Pneumococcus</td>
<td>S. Pneumoniae Cell Wall Polysaccharide Antigen</td>
<td>Poliovirus</td>
<td>Type 2</td>
<td>Capsid protein VP3-VP1</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Tetanus</td>
<td>Clostridium tetani Tetanus Toxoid</td>
<td>Poliovirus</td>
<td>Type 3</td>
<td>Capsid protein VP3-VP1</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Tetanus</td>
<td>Tetanus Toxoid, Recombinant Heavy Chain Fragment C</td>
<td>Respiratory Syncytial Virus (RSV)</td>
<td>RSVA</td>
<td>Glycoprotein G</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Hepatit-B</td>
<td>HBV Surface Antigen (subtype adw)</td>
<td>Rotavirus</td>
<td>Strain Rotavirus A/RVA/Vaccine/USA/Rotarix-AROLA490AB/1988/G1P1A</td>
<td>Glycoprotein VP7</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Poliovirus </td>
<td>Recombinant Poliovirus type 1 Capsid protein (strain Sabin)</td>
<td>Rotavirus</td>
<td>Strain SA-11</td>
<td></td>
<td></td>
<td>MA 104 cells</td>
</tr>
<tr>
<td>Poliovirus </td>
<td>Recombinant Poliovirus type 2 VP3-VP1 capsid Protein [His]</td>
<td>Rubella Virus</td>
<td></td>
<td></td>
<td>Grade 4 antigen</td>
<td></td>
</tr>
<tr>
<td>Poliovirus </td>
<td>Recombinant Poliovirus type 3 VP3-VP1 capsid protein</td>
<td>Rubella Virus</td>
<td>Strain F-Therien</td>
<td>Nucleoprotein</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Cytomegalovirus (CMV)</td>
<td>Cytomegalovirus glycoprotein B (gB)</td>
<td>Rubella Virus</td>
<td></td>
<td>Glycoprotein E1</td>
<td></td>
<td>E. coli</td>
</tr>
<tr>
<td>Epstein–Barr virus (EBV)</td>
<td>Epstein Barr Virus gp125</td>
<td>Rubella Virus</td>
<td>Strain F-Therien</td>
<td>Spike glycoprotein E1</td>
<td></td>
<td>HEK</td>
</tr>
<tr>
<td>Epstein–Barr virus (EBV)</td>
<td>Epstein–Barr nuclear antigen 1</td>
<td>Rubella Virus</td>
<td>Strain HPV-77</td>
<td>Spike glycoprotein E1 & E2</td>
<td>Rubella Vaccine</td>
<td>Insect cells</td>
</tr>
<tr>
<td>Respiratory syncytial</td>
<td>Respiratory Syncytial Virus A Glycoprotein G</td>
<td>Streptococcus Pneumoniae</td>
<td></td>
<td>Cell wall polysaccharide antigen</td>
<td>Native</td>
<td></td>
</tr>
<tbody>
</tbody>
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