This is a Genome-wide Epigenetic Efficiency Profiling tool which estimates methylation efficiencies over time given bisulfite and oxidative bisulfite sequencing data. The tool can predict the efficiencies of maintenance, de-novo and hydroxyl-methylation of single CpGs and infer the methylation levels. The efficiencies are modeled using a Hidden Markov model and the estimation of these parameters is done using Bayesian Inference.