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PMID:31501141 Trichophyton rubrum Azole Resistance Mediated by a New ABC Transporter, TruMDR3. #53
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help #175908] [uuw] UniProtKB/TrEMBL F2SG60 entry update request Now done by Marc Feuermann 18/11/2019 |
Hi @ValWood Please could you check this very short chemistry curation session. I'm not sure the best way of capturing the phenotype here as its not clear what to use as the control
What should we use as the control? Also to note: UniProt appears to have 2 refernce strains here but I assume we focus on the top entry strain as this matches the UniProt id obtained from the gene id provided in the paper (TERG_02186). |
my assumption is that any mutant is compared to WT of the same strsain. So here I think "sensitive to x" is OK. I guess more annotation could be made for this paper if we had a better way to do the ectopic expression .... |
+id: GO:0140394 |
I have used the new above term to replace the previously used GO term in the session. |
Looks like this basic Tier 1 level curation session is complete. |
Session approved, closing ticket. |
Check new 'chemistry phenotype' terms. may need NTR: normal growth chemical X |
No need. Closing ticket. |
Title of publication calls gene TruMDR3 UniProt gene name MDR3 and so the GO annotations use MDR3 Hi @ValWood, do you think we need the species prefix at the beginning of the gene name in the genotype? Should the genotype also just be MDR3::nptII+(disruption) in stead of TruMDR3::nptII+(disruption)? |
It is OK to put the genotype name as the authors named it, as long as the description is standardized (i.e disruption), and it is linked to the official gene name. |
Thanks for confirming this :-). |
no archetype information found |
Link to curation session
https://canto.phi-base.org/curs/b06680e815f64df0
Suggest by author 'Marc Feuermann' from Swiss-prot
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