Active transports Lumen<=> Mucosa: too many transports are created in case the transporter direction (Influx/Efflux/...) is not the same in all GI segments.

[Yuri05]

In the project attached, different transporter directions were defined in GI segments: Mucosa_MultipleTransportDirections.zip

In the created simulation, each GI-segment gets transports of each direction defined for any GI segment, which is obviously wrong:

The problem is: transport source/target descriptor conditions are not properly extended:

In the tissue organs this is done correctly. E.g. in the same project different transporter directions are defined for some tissue organs:

In the simulation exactly 1 transport of selected type is created per organ:

This is because the transport source/target criteria are properly extended:

Thus the problem exists only for Lumen <=> Mucosa transports

[msevestre]

v10.1 or v11? e.g. are we going to release a patch for this?

[msevestre]

Looking at this now

[msevestre]

This is because of this line
https://github.com/Open-Systems-Pharmacology/PK-Sim/blob/develop/src/PKSim.Core/Mappers/ProcessToProcessBuilderMapper.cs#L375