Version 11.0
This release contains the OSP qualification reports. All reports are created with OSP 11 and are available here.
Release Notes
New Qualification Reports
CYP1A2 DDI
This qualification report evaluates the developed PBPK drug-drug interactions (DDI) models network for the ability to perform simulations with the intended purpose to predict cytochrome P450 1A2 (CYPA12)-mediated DDI.
CYP2C19 DDI
This qualification report evaluates the developed PBPK drug-drug interactions (DDI) models network for the ability to perform simulations with the intended purpose to predict cytochrome P450 2C19 (CYP2C19)-mediated DDI.
Updates
UGT DDI Qualification Report
Minor updates
- Fixed wrong chapter content assignment (Open-Systems-Pharmacology/Qualification-DDI-UGT#14)
Pediatric Qualification Report: CYP2C8 Ontogeny
Minor updates
- updated reference to new OSP PK database release (v1.4)
- minor editorial updates and bug fixes (typos, broken links)
Pediatric Qualification Report: CYP3A4 Ontogeny
Minor updates
- updated reference to new OSP PK database release (v1.4)
- minor editorial updates and bug fixes (typos, broken links)
Pediatric Qualification Report: GFR Ontogeny
Minor updates
- updated reference to new OSP PK database release (v1.4)
- minor editorial updates and bug fixes (typos, broken links)