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@Yuri05 Yuri05 released this 23 May 07:29
· 10 commits to master since this release
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This release contains the OSP qualification reports. All reports are created with OSP 11 and are available here.

Release Notes

New Qualification Reports

CYP1A2 DDI

This qualification report evaluates the developed PBPK drug-drug interactions (DDI) models network for the ability to perform simulations with the intended purpose to predict cytochrome P450 1A2 (CYPA12)-mediated DDI.

CYP2C19 DDI

This qualification report evaluates the developed PBPK drug-drug interactions (DDI) models network for the ability to perform simulations with the intended purpose to predict cytochrome P450 2C19 (CYP2C19)-mediated DDI.

Updates

UGT DDI Qualification Report

Minor updates

Pediatric Qualification Report: CYP2C8 Ontogeny

Minor updates

  • updated reference to new OSP PK database release (v1.4)
  • minor editorial updates and bug fixes (typos, broken links)

Pediatric Qualification Report: CYP3A4 Ontogeny

Minor updates

  • updated reference to new OSP PK database release (v1.4)
  • minor editorial updates and bug fixes (typos, broken links)

Pediatric Qualification Report: GFR Ontogeny

Minor updates

  • updated reference to new OSP PK database release (v1.4)
  • minor editorial updates and bug fixes (typos, broken links)