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We are experiencing an issue with the retention of expected replicates when one of the samples fails the call rate filters. Specifically, if we have two samples that are expected replicates and one does not pass the call rate filter, the other sample that does pass should still be retained and proceed to subject-level qc.
This did not happen in the case below though. We would expect to retain SB745670_PB84781_G01 since its counterpart SB745670_PB84781_F05 had a low call rate.
Sample_ID
Group_By_Subject_ID
Project
Case/Control_Status
Internal Control
Number Samples Per Subject
Replicate IDs
Sample Excluded from QC
Sample Used in Subject Analysis
Subject Removed
Sample Pass QC
Low Call Rate
SB745670_PB84781_G01
I-0000618499
GP0385-CI21
Control
FALSE
2
SB745670_PB84781_F05|SB745670_PB84781_G01
FALSE
FALSE
TRUE
FALSE
FALSE
SB745670_PB84781_F05
I-0000618499
GP0385-CI21
Control
FALSE
2
SB745670_PB84781_F05|SB745670_PB84781_G01
FALSE
FALSE
TRUE
FALSE
TRUE
The text was updated successfully, but these errors were encountered:
We are experiencing an issue with the retention of expected replicates when one of the samples fails the call rate filters. Specifically, if we have two samples that are expected replicates and one does not pass the call rate filter, the other sample that does pass should still be retained and proceed to subject-level qc.
This did not happen in the case below though. We would expect to retain
SB745670_PB84781_G01
since its counterpartSB745670_PB84781_F05
had a low call rate.The text was updated successfully, but these errors were encountered: