Implementation constraint queries

[tursynay]

Each aras should be assigned, if they cannot do it, they can call it out of scope and we can assign them later.

[tursynay]

Workflow query A.1 - write a query with a TRAPI constraint with a chemical that must be FDA approved. Along the way ARAs and ARS will then know what to do. Currently none of the ARAs are implementing constraints. The idea is to have the ARAs implement the constraint. There is a backup plan that this constraint can be implemented with workflow runner and then ARAs don't have to worry about it. But before the backup plan is implemented, ARAs need to evaluate and determine if implementing the constraint is out of scope for them. @vgardner-renci, assign all ARAs to this issue so they can make a decision.

[andrewsu]

BTE is planning on implementing constraint filtering, tracked in biothings/biothings_explorer#174

[amykglen]

ARAX is planning to have this constraint implemented by Aug. 20 - being tracked in RTXteam/RTX#1599

[webyrd]

Will triage by August 12, 2021. We have some limited constraint capabilities already. I need to investigate what else we'd need to add.

[tursynay]

In the mini hackathon repo, there is a folder with code EFGR advanced.

[cbizon]

This is in-scope for ranking-agent. Being tracked: ranking-agent/strider#233

[andrewsu]

the example TRAPI query with the constraint is here: https://github.com/NCATSTranslator/minihackathons/blob/main/2021-12_demo/workflowA/EGFR_advanced.json

[vgardner-renci]

Improving Agent and Explanatory Agent folks, can you comment on this issue @brettasmi @jenndoug @suihuang-ISB @Rosinaweber

[amykglen]

ARAX has implemented handling of the biolink:highest_FDA_approval_status constraint (as defined in A.9_EGFR_advanced.json) - an example of a query using it is here: https://arax.ncats.io/?r=19693

Has there been a discussion about what possible values other than "regular approval" this constraint might have? We have other drug status information like "experimental drug" or "investigational drug" that could be constrained on as well, but are not sure if a standard way of creating constraints for such info has been settled on.

[webyrd]

Will implement by the relay.

[cbizon]

Strider being deployed Sep 9 should implement this.

[brettasmi]

On our to-dos and will be implemented by relay.

edit: finished for FDA approval

@vgardner-renci can you remove myself, @jenndoug, @suihuang-ISB, and @baranzini-lab? Thanks!