GitHub - ModelDBRepository/262115: NN activity impact on neocortical pyr. neurons integrative properties in vivo (Destexhe & Pare 1999)

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NN activity impact on neocortical pyr. neurons integrative properties in vivo (Destexhe & Pare 1999)

modeldb.science/262115

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Name		Name	Last commit message	Last commit date
Latest commit History 7 Commits
Electrode.oc		Electrode.oc
IKd_traub.mod		IKd_traub.mod
IM_zach.mod		IM_zach.mod
INa_traub_shifted.mod		INa_traub_shifted.mod
README.html		README.html
add_just_axon.oc		add_just_axon.oc
corrgen8.mod		corrgen8.mod
corrgen8.mod.windows		corrgen8.mod.windows
demo_bombardment_active_coarse.oc		demo_bombardment_active_coarse.oc
demo_bombardment_active_precise.oc		demo_bombardment_active_precise.oc
demo_bombardment_passive_coarse.oc		demo_bombardment_passive_coarse.oc
demo_bombardment_passve_precise.oc		demo_bombardment_passve_precise.oc
init.hoc		init.hoc
layer6.geo		layer6.geo
localize_currents_M.oc		localize_currents_M.oc
localize_synapses_corrgen_mul.oc		localize_synapses_corrgen_mul.oc
mosinit.hoc		mosinit.hoc
multiAMPA.mod		multiAMPA.mod
multiGABAa.mod		multiGABAa.mod
multiNMDA.mod		multiNMDA.mod
screenshot.png		screenshot.png

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<html>
<p>This demo simulates synaptic bombardment of "in vivo like" conditions
in neocortical pyramidal neurons, based on the model detailed in 
</p>
<p>Destexhe, A. and Pare D.  Impact of network activity on the integrative 
properties of neocortical pyramidal neurons in vivo. J. Neurophysiol.
  81: 1531-1547, 1999.<br/>
  doi: <a href="http://dx.doi.org/10.1152/jn.1999.81.4.1531">10.1152/jn.1999.81.4.1531</a>
</p>
<p>These model files were contributed by A Destexhe. A PDF copy of this paper is available in <a href="http://cns.iaf.cnrs-gif.fr">http://cns.iaf.cnrs-gif.fr</a>
</p>
<p>(see this paper for all details)</p>
Usage:<br/>
------<br/>
Compile the mod files with nrnivmodl (linux); for additional platforms
(for microsoft windows replace corrgen8.mod with corrgen8.mod.windows before compiling mod files) and detailed help please consult the following if needed:<br/>
<a href="https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide">https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide</a><p/>
Start with a command like:<p/>
nrngui mosinit.hoc
<p/>Select a simulation to run from the buttons in the GUI<p/>
For example selecting "Active precise", and then
"Run + calc histogram" should create the following figures<p/>
<img src="./screenshot.png" alt="screenshot">
<br><br><br>
  <u>Changelog</u>
  <ul>
    <li>20220924: Update MOD files to avoid declaring variables and functions with the same name.
  See <a href="https://github.com/neuronsimulator/nrn/pull/1992">https://github.com/neuronsimulator/nrn/pull/1992</a>
    </li>
  </ul>

</html>