Building and Running the cBioPortal Docker Container 1. Build the Docker Image: docker build -t cbioportal . This can take a long time to complete, as it will download and build all the dependencies required to run the cBioPortal application. 2. Run the Docker Container: docker run -p 8080:8080 cbioportal On first startup this will take a while to complete, because it needs to set up the database 3. Open the application: http://localhost:8080