Major updates
- Requirement changed
- g++ >=7 (>=7.3 recommended)
- cmake >=3.14
- samtools >=1.13 (using htslib >=1.13)
- BAM mode accelerated
- CRAM support
Minor bugs fixed
Simplified sample (tumor) specific read collection step
ETCHING was a bit slow in removing remaining germline SVs after scoring SVs. We solved this issue by increasing Samtools requirement to >=1.13 for collecting the paired-end reads relevant to the remaining artifacts. As we updated the step, we accelerated the workflow for BAM input and added CRAM support (please see ETCHING_v1.4.2_workflow.png/pdf).