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Ruff lint, format, sort imports
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dnil committed Nov 27, 2024
1 parent ea2592c commit d24ffc3
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4 changes: 2 additions & 2 deletions genmod/annotate_models/__init__.py
Original file line number Diff line number Diff line change
@@ -1,7 +1,7 @@
from __future__ import absolute_import

from .make_haploblocks import get_haploblocks
from .fix_variant import make_print_version
from .genetic_models import check_genetic_models
from .make_haploblocks import get_haploblocks
from .model_score import get_model_score
from .fix_variant import make_print_version
from .variant_annotator import VariantAnnotator
84 changes: 36 additions & 48 deletions genmod/annotate_models/fix_variant.py
Original file line number Diff line number Diff line change
@@ -1,90 +1,78 @@
from . import get_model_score


def make_print_version(variant, families):
"""
Get the variants ready for printing
This function collects the annotations added and merge them in the INFO
dict.
Arguments:
variant (dict): A variant dictionary
"""
variant_id = variant['variant_id']
vcf_info = variant['INFO'].split(';')
feature_list = variant.get('annotation', set())

variant_id = variant["variant_id"]
vcf_info = variant["INFO"].split(";")

feature_list = variant.get("annotation", set())

# variant[compounds] is a dictionary with family id as keys and a set of compounds as values
compounds = variant.get('compounds', dict())
compounds = variant.get("compounds", dict())
# Here we store the compound strings that should be added to the variant:
family_compound_strings = []

genetic_models = variant.get('inheritance_models', {})
genetic_models = variant.get("inheritance_models", {})

# We need to check if compounds have already been annotated.
if 'Compounds' not in variant['info_dict']:

if "Compounds" not in variant["info_dict"]:
for family_id in compounds:
if (genetic_models[family_id].get('AR_comp') or genetic_models[family_id].get('AR_comp_dn')):
compound_string = ''
if genetic_models[family_id].get("AR_comp") or genetic_models[family_id].get(
"AR_comp_dn"
):
compound_string = ""
compound_set = compounds[family_id]
#We do not want reference to itself as a compound:
# We do not want reference to itself as a compound:
compound_set.discard(variant_id)
# If there are any compounds for the family:
if compounds[family_id]:
compound_string = '|'.join(compound_set)
family_compound_strings.append(':'.join([family_id, compound_string]))
compound_string = "|".join(compound_set)
family_compound_strings.append(":".join([family_id, compound_string]))

if len(family_compound_strings) > 0:
vcf_info.append('Compounds=' + ','.join(family_compound_strings))
vcf_info.append("Compounds=" + ",".join(family_compound_strings))

# Check if any genetic models are followed
if 'GeneticModels' not in variant['info_dict']:
if "GeneticModels" not in variant["info_dict"]:
# Here we store the compound strings that should be added to the variant:
family_model_strings = []
model_scores = {}
for family_id in genetic_models:
model_string = ''
model_string = ""
model_list = []
for model in genetic_models[family_id]:
if genetic_models[family_id][model]:
model_list.append(model)
model_string = '|'.join(model_list)
model_string = "|".join(model_list)
if len(model_list) > 0:
family_model_strings.append(':'.join(
[family_id, model_string]))

family_model_strings.append(":".join([family_id, model_string]))

model_scores[family_id] = str(
get_model_score(families[family_id].individuals, variant))

get_model_score(families[family_id].individuals, variant)
)

if len(family_model_strings) > 0:
vcf_info.append(
'GeneticModels={0}'.format(
','.join(family_model_strings)))
vcf_info.append("GeneticModels={0}".format(",".join(family_model_strings)))

model_score_list = []
for family_id in model_scores:
if model_scores[family_id]:
if float(model_scores[family_id]) > 0:
model_score_list.append(
':'.join(
[
family_id,
model_scores[family_id]
]
)
)
model_score_list.append(":".join([family_id, model_scores[family_id]]))
if len(model_score_list) > 0:
vcf_info.append(
'ModelScore=' +
','.join(model_score_list)
)



variant['INFO'] = ';'.join(vcf_info)
vcf_info.append("ModelScore=" + ",".join(model_score_list))

variant["INFO"] = ";".join(vcf_info)

return variant
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