Colon coordinates

src/scaffoldmaker/annotation/colon_terms.py

@@ -7,10 +7,13 @@
     ( "ascending colon", "UBERON:0001156", "FMA:14545", "ILX:0734393"),
     ( "descending colon", "UBERON:0001158", "FMA:14547", "ILX:0724444"),
     ( "caecum", "UBERON:0001153", "FMA:14541", "ILX:0732270"),
+    ( "Circular muscle layer of colon", "ILX:0772428"),
     ( "colon", "UBERON:0001155", "FMA:14543", "ILX:0736005"),
     ( "colonic mucosa", "UBERON:0000317", "FMA:14984", "ILX:0731046"),
     ( "distal colon", "UBERON:0008971", "ILX:0727523"),
+    ( "Longitudinal muscle layer of colon", "ILX:0775554"),
     ( "mesenteric zone", "None"),
+    ( "myenteric nerve plexus", "UBERON:0002439", "FMA:63252", "ILX:0725342"),
     ( "non-mesenteric zone", "None"),
     ( "proximal colon", "UBERON:0008972", "ILX:0733240"),
     ( "serosa of colon", "UBERON:0003335", "FMA:14990", "ILX:0736932"),

src/scaffoldmaker/meshtypes/meshtype_3d_bladderurethra1.py

@@ -860,9 +860,11 @@ def generateBaseMesh(cls, region, options):
             wallThicknessList = [bladderWallThickness] * (elementsCountAlong + 1)
         transitElementList = [0] * elementsCountAround
 
+        relativeThicknessList = []
         xList, d1List, d2List, d3List, curvatureList = tubemesh.getCoordinatesFromInner(xWarpedList, d1WarpedList,
                                                                                         d2WarpedList, d3WarpedUnitList,
                                                                                         wallThicknessList,
+                                                                                        relativeThicknessList,
                                                                                         elementsCountAround,
                                                                                         elementsCountAlong,
                                                                                         elementsCountThroughWall,
@@ -902,8 +904,8 @@ def generateBaseMesh(cls, region, options):
         d2Final += d2List[(elementsCountThroughWall + 1) * elementsCountAround:]
         d3Final += d3List[(elementsCountThroughWall + 1) * elementsCountAround:]
 
-        xFlat = d1Flat = d2Flat = d3Flat = []
-        xTexture = d1Texture = d2Texture = d3Texture = []
+        xFlat = d1Flat = d2Flat = []
+        xOrgan = d1Organ = d2Organ = []
 
         # Obtain elements count along body and neck of the bladder for defining annotation groups
         elementsCountAlongBody = round(ureterPositionDown * elementsCountAlongBladder - 1)
@@ -1004,7 +1006,7 @@ def generateBaseMesh(cls, region, options):
 
         # Create nodes and elements
         nextNodeIdentifier, nextElementIdentifier, annotationGroups = tubemesh.createNodesAndElements(
-            region, xFinal, d1Final, d2Final, d3Final, xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture,
+            region, xFinal, d1Final, d2Final, d3Final, xFlat, d1Flat, d2Flat, xOrgan, d1Organ, d2Organ, None,
             elementsCountAround, elementsCountAlong, elementsCountThroughWall,
             annotationGroupsAround, annotationGroupsAlong, annotationGroupsThroughWall,
             firstNodeIdentifier, firstElementIdentifier,

src/scaffoldmaker/meshtypes/meshtype_3d_cecum1.py

@@ -430,8 +430,9 @@ def generateBaseMesh(cls, region, options):
         # Create coordinates and derivatives
         wallThicknessList = [wallThickness] * (elementsCountAlong + 1)
 
+        relativeThicknessList = []
         xList, d1List, d2List, d3List, curvatureList = tubemesh.getCoordinatesFromInner(xWarpedList, d1WarpedList,
-            d2WarpedList, d3WarpedUnitList, wallThicknessList,
+            d2WarpedList, d3WarpedUnitList, wallThicknessList, relativeThicknessList,
             elementsCountAround, elementsCountAlong, elementsCountThroughWall, transitElementList)
 
         # Deal with multiple nodes at end point for closed proximal end
@@ -463,8 +464,8 @@ def generateBaseMesh(cls, region, options):
         d2Cecum += d2List[(elementsCountThroughWall + 1) * elementsCountAround:]
         d3Cecum += d3List[(elementsCountThroughWall + 1) * elementsCountAround:]
 
-        xFlat = d1Flat = d2Flat = d3Flat = []
-        xTexture = d1Texture = d2Texture = d3Texture = []
+        xFlat = d1Flat = d2Flat = []
+        xOrgan = d1Organ = d2Organ = []
 
         # Create nodes and elements
         if tcThickness > 0:
@@ -475,15 +476,15 @@ def generateBaseMesh(cls, region, options):
                 tubeTCWidthList, tcThickness, sxRefList, annotationGroupsAround, closedProximalEnd)
 
             nextNodeIdentifier, nextElementIdentifier, annotationGroups = createNodesAndElementsTeniaColi(
-                    region, xCecum, d1Cecum, d2Cecum, d3Cecum, xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture,
+                    region, xCecum, d1Cecum, d2Cecum, d3Cecum, xFlat, d1Flat, d2Flat, xOrgan, d1Organ, d2Organ, None,
                     elementsCountAroundTC, elementsCountAroundHaustrum, elementsCountAlong, elementsCountThroughWall,
                     tcCount, annotationGroupsAround, annotationGroupsAlong, annotationGroupsThroughWall,
                     firstNodeIdentifier, firstElementIdentifier, useCubicHermiteThroughWall, useCrossDerivatives,
                     closedProximalEnd)
 
         else:
             nextNodeIdentifier, nextElementIdentifier, annotationGroups = tubemesh.createNodesAndElements(
-                region, xCecum, d1Cecum, d2Cecum, d3Cecum, xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture,
+                region, xCecum, d1Cecum, d2Cecum, d3Cecum, xFlat, d1Flat, d2Flat, xOrgan, d1Organ, d2Organ, None,
                 elementsCountAround, elementsCountAlong, elementsCountThroughWall,
                 annotationGroupsAround, annotationGroupsAlong, annotationGroupsThroughWall,
                 firstNodeIdentifier, firstElementIdentifier, useCubicHermiteThroughWall, useCrossDerivatives,

src/scaffoldmaker/meshtypes/meshtype_3d_colon1.py

@@ -5,11 +5,12 @@
 """
 
 import copy
-from scaffoldmaker.annotation.annotationgroup import AnnotationGroup
+from opencmiss.zinc.element import Element
+from scaffoldmaker.annotation.annotationgroup import AnnotationGroup, findOrCreateAnnotationGroupForTerm, getAnnotationGroupForTerm
 from scaffoldmaker.annotation.colon_terms import get_colon_term
 from scaffoldmaker.meshtypes.meshtype_1d_path1 import MeshType_1d_path1, extractPathParametersFromRegion
 from scaffoldmaker.meshtypes.meshtype_3d_colonsegment1 import MeshType_3d_colonsegment1, ColonSegmentTubeMeshInnerPoints,\
-    getTeniaColi, createFlatAndTextureCoordinatesTeniaColi, createNodesAndElementsTeniaColi
+    getTeniaColi, createFlatCoordinatesTeniaColi, createColonCoordinatesTeniaColi, createNodesAndElementsTeniaColi
 from scaffoldmaker.meshtypes.scaffold_base import Scaffold_base
 from scaffoldmaker.scaffoldpackage import ScaffoldPackage
 from scaffoldmaker.utils import interpolation as interp
@@ -313,11 +314,11 @@ def getDefaultOptions(cls, parameterSetName='Default'):
             options['Proximal inner radius'] = 1.0
             options['Proximal tenia coli width'] = 0.5
             options['Proximal-transverse inner radius'] = 0.9
-            options['Proximal-transverse tenia coli width'] = 0.7
+            options['Proximal-transverse tenia coli width'] = 0.5
             options['Transverse-distal inner radius'] = 0.7
-            options['Transverse-distal tenia coli width'] = 1.0
+            options['Transverse-distal tenia coli width'] = 0.5
             options['Distal inner radius'] = 0.7
-            options['Distal tenia coli width'] = 1.0
+            options['Distal tenia coli width'] = 0.5
         elif 'Pig 1' in parameterSetName:
             options['Number of segments'] = 120
             options['Proximal length'] = 3000.0
@@ -471,10 +472,19 @@ def generateBaseMesh(cls, region, options):
         elementsCountAlongSegment = segmentSettings['Number of elements along segment']
         elementsCountThroughWall = segmentSettings['Number of elements through wall']
         wallThickness = segmentSettings['Wall thickness']
+        mucosaRelThickness = segmentSettings['Mucosa relative thickness']
+        submucosaRelThickness = segmentSettings['Submucosa relative thickness']
+        circularRelThickness = segmentSettings['Circular muscle layer relative thickness']
+        longitudinalRelThickness = segmentSettings['Longitudinal muscle layer relative thickness']
         useCrossDerivatives = segmentSettings['Use cross derivatives']
         useCubicHermiteThroughWall = not(segmentSettings['Use linear through wall'])
         elementsCountAlong = int(elementsCountAlongSegment*segmentCount)
 
+        # Colon coordinates
+        lengthToDiameterRatio = 24
+        wallThicknessToDiameterRatio = 0.1
+        teniaColiThicknessToDiameterRatio = 0.005
+
         firstNodeIdentifier = 1
         firstElementIdentifier = 1
 
@@ -565,16 +575,21 @@ def generateBaseMesh(cls, region, options):
             for n in range(elementsCount):
                 annotationGroupsAlong.append(annotationGroupAlong[i])
 
-        annotationGroupsThroughWall = []
-        for i in range(elementsCountThroughWall):
-            annotationGroupsThroughWall.append([ ])
+        mucosaGroup = AnnotationGroup(region, get_colon_term("colonic mucosa"))
+        submucosaGroup = AnnotationGroup(region, get_colon_term("submucosa of colon"))
+        circularMuscleGroup = AnnotationGroup(region, get_colon_term("Circular muscle layer of colon"))
+        longitudinalMuscleGroup = AnnotationGroup(region, get_colon_term("Longitudinal muscle layer of colon"))
+        annotationGroupsThroughWall = [[mucosaGroup], [submucosaGroup], [circularMuscleGroup], [longitudinalMuscleGroup]]
 
         xExtrude = []
         d1Extrude = []
         d2Extrude = []
         d3UnitExtrude = []
         sxRefExtrudeList = []
 
+        relativeThicknessList = [mucosaRelThickness, submucosaRelThickness, circularRelThickness,
+                                 longitudinalRelThickness]
+
         # Create object
         colonSegmentTubeMeshInnerPoints = ColonSegmentTubeMeshInnerPoints(
             region, elementsCountAroundTC, elementsCountAroundHaustrum, elementsCountAlongSegment,
@@ -613,7 +628,7 @@ def generateBaseMesh(cls, region, options):
 
         # Create coordinates and derivatives
         xList, d1List, d2List, d3List, curvatureList = tubemesh.getCoordinatesFromInner(xExtrude, d1Extrude,
-            d2Extrude, d3UnitExtrude, contractedWallThicknessList,
+            d2Extrude, d3UnitExtrude, contractedWallThicknessList, relativeThicknessList,
             elementsCountAround, elementsCountAlong, elementsCountThroughWall, transitElementList)
 
         relaxedLengthList, xiList = colonSegmentTubeMeshInnerPoints.getRelaxedLengthAndXiList()
@@ -628,30 +643,48 @@ def generateBaseMesh(cls, region, options):
                 tubeTCWidthList, tcThickness, sxRefExtrudeList, annotationGroupsAround,
                 closedProximalEnd)
 
-            # Create flat and texture coordinates
-            xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture = createFlatAndTextureCoordinatesTeniaColi(
-                xiList, relaxedLengthList, length, wallThickness, tcCount, tcThickness,
+            # Create flat coordinates
+            xFlat, d1Flat, d2Flat = createFlatCoordinatesTeniaColi(
+                xiList, relaxedLengthList, length, wallThickness, relativeThicknessList, tcCount, tcThickness,
                 elementsCountAroundTC, elementsCountAroundHaustrum, elementsCountAlong,
                 elementsCountThroughWall, transitElementList, closedProximalEnd)
 
+            # Create colon coordinates
+            xColon, d1Colon, d2Colon = createColonCoordinatesTeniaColi(xiList, relativeThicknessList,
+                                                                       lengthToDiameterRatio,
+                                                                       wallThicknessToDiameterRatio,
+                                                                       teniaColiThicknessToDiameterRatio, tcCount,
+                                                                       elementsCountAroundTC,
+                                                                       elementsCountAroundHaustrum,
+                                                                       elementsCountAlong, elementsCountThroughWall,
+                                                                       transitElementList, closedProximalEnd)
+
             # Create nodes and elements
             nextNodeIdentifier, nextElementIdentifier, annotationGroups = createNodesAndElementsTeniaColi(
-                region, xList, d1List, d2List, d3List, xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture,
-                elementsCountAroundTC, elementsCountAroundHaustrum, elementsCountAlong, elementsCountThroughWall,
-                tcCount, annotationGroupsAround, annotationGroupsAlong, annotationGroupsThroughWall,
-                firstNodeIdentifier, firstElementIdentifier, useCubicHermiteThroughWall, useCrossDerivatives,
-                closedProximalEnd)
+                region, xList, d1List, d2List, d3List, xFlat, d1Flat, d2Flat, xColon, d1Colon, d2Colon,
+                "colon coordinates", elementsCountAroundTC, elementsCountAroundHaustrum, elementsCountAlong,
+                elementsCountThroughWall, tcCount, annotationGroupsAround, annotationGroupsAlong,
+                annotationGroupsThroughWall, firstNodeIdentifier, firstElementIdentifier, useCubicHermiteThroughWall,
+                useCrossDerivatives, closedProximalEnd)
 
         else:
-            # Create flat and texture coordinates
-            xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture = tubemesh.createFlatAndTextureCoordinates(
-                xiList, relaxedLengthList, length, wallThickness, elementsCountAround,
+            # Create flat coordinates
+            xFlat, d1Flat, d2Flat = tubemesh.createFlatCoordinates(
+                xiList, relaxedLengthList, length, wallThickness, relativeThicknessList, elementsCountAround,
                 elementsCountAlong, elementsCountThroughWall, transitElementList)
 
+            # Create colon coordinates
+            xColon, d1Colon, d2Colon = tubemesh.createOrganCoordinates(xiList, relativeThicknessList,
+                                                                       lengthToDiameterRatio,
+                                                                       wallThicknessToDiameterRatio,
+                                                                       elementsCountAround,
+                                                                       elementsCountAlong, elementsCountThroughWall,
+                                                                       transitElementList)
+
             # Create nodes and elements
             nextNodeIdentifier, nextElementIdentifier, annotationGroups = tubemesh.createNodesAndElements(
-                region, xList, d1List, d2List, d3List, xFlat, d1Flat, d2Flat, xTexture, d1Texture, d2Texture,
-                elementsCountAround, elementsCountAlong, elementsCountThroughWall,
+                region, xList, d1List, d2List, d3List, xFlat, d1Flat, d2Flat, xColon, d1Colon, d2Colon,
+                "colon coordinates", elementsCountAround, elementsCountAlong, elementsCountThroughWall,
                 annotationGroupsAround, annotationGroupsAlong, annotationGroupsThroughWall,
                 firstNodeIdentifier, firstElementIdentifier, useCubicHermiteThroughWall, useCrossDerivatives,
                 closedProximalEnd)
@@ -672,3 +705,35 @@ def refineMesh(cls, meshrefinement, options):
         meshrefinement.refineAllElementsCubeStandard3d(refineElementsCountAround, refineElementsCountAlong,
                                                        refineElementsCountThroughWall)
         return
+
+    @classmethod
+    def defineFaceAnnotations(cls, region, options, annotationGroups):
+        '''
+        Add face annotation groups from the highest dimension mesh.
+        Must have defined faces and added subelements for highest dimension groups.
+        :param region: Zinc region containing model.
+        :param options: Dict containing options. See getDefaultOptions().
+        :param annotationGroups: List of annotation groups for top-level elements.
+        New face annotation groups are appended to this list.
+        '''
+        # Create 2d surface mesh groups
+        fm = region.getFieldmodule()
+        longitudinalMuscleGroup = getAnnotationGroupForTerm(annotationGroups,
+                                                            get_colon_term("Longitudinal muscle layer of colon"))
+        circularMuscleGroup = getAnnotationGroupForTerm(annotationGroups,
+                                                        get_colon_term("Circular muscle layer of colon"))
+        mesh2d = fm.findMeshByDimension(2)
+        is_exterior = fm.createFieldIsExterior()
+        is_exterior_face_xi3_1 = fm.createFieldAnd(is_exterior, fm.createFieldIsOnFace(Element.FACE_TYPE_XI3_1))
+
+        is_longitudinalMuscle = longitudinalMuscleGroup.getFieldElementGroup(mesh2d)
+        is_serosa = fm.createFieldAnd(is_longitudinalMuscle, is_exterior_face_xi3_1)
+        is_circularMuscle = circularMuscleGroup.getFieldElementGroup(mesh2d)
+        is_myentericPlexus = fm.createFieldAnd(is_longitudinalMuscle, is_circularMuscle)
+
+        serosa = findOrCreateAnnotationGroupForTerm(annotationGroups, region, get_colon_term("serosa of colon"))
+        serosa.getMeshGroup(mesh2d).addElementsConditional(is_serosa)
+
+        myentericPlexus = findOrCreateAnnotationGroupForTerm(annotationGroups, region,
+                                                             get_colon_term("myenteric nerve plexus"))
+        myentericPlexus.getMeshGroup(mesh2d).addElementsConditional(is_myentericPlexus)