diff --git a/src/bindings/python/constraints.txt b/src/bindings/python/constraints.txt
index 582da3f7250926..044728229b54e8 100644
--- a/src/bindings/python/constraints.txt
+++ b/src/bindings/python/constraints.txt
@@ -1,7 +1,7 @@
 # used in multiple components
 onnx==1.13.1  # Python bindings, ONNX Frontend
 numpy>=1.16.6,<1.25  # Python bindings, frontends
-protobuf>=3.18.1,<4.0.0  # Python bindings, frontends
+protobuf>=3.18.1,<5.0.0  # Python bindings, frontends
 
 # pytest
 pytest>=5.0,<7.4