diff --git a/changelog.md b/changelog.md
index 1ecd4cdaa7..9d68531972 100644
--- a/changelog.md
+++ b/changelog.md
@@ -27,6 +27,7 @@
 * [2867](https://github.com/zeta-chain/node/pull/2867) - skip precompiles test for tss migration
 * [2833](https://github.com/zeta-chain/node/pull/2833) - add e2e framework for TON blockchain
 * [2874](https://github.com/zeta-chain/node/pull/2874) - add support for multiple runs for precompile tests
+* [2895](https://github.com/zeta-chain/node/pull/2895) - add e2e test for bitcoin deposit and call
 * [2894](https://github.com/zeta-chain/node/pull/2894) - increase gas limit for TSS vote tx
 
 ### Fixes
diff --git a/cmd/zetae2e/local/local.go b/cmd/zetae2e/local/local.go
index 7e31d4a407..d84a4ba9a4 100644
--- a/cmd/zetae2e/local/local.go
+++ b/cmd/zetae2e/local/local.go
@@ -290,6 +290,7 @@ func localE2ETest(cmd *cobra.Command, _ []string) {
 
 		bitcoinTests := []string{
 			e2etests.TestBitcoinDepositName,
+			e2etests.TestBitcoinDepositAndCallName,
 			e2etests.TestBitcoinDepositRefundName,
 			e2etests.TestBitcoinWithdrawSegWitName,
 			e2etests.TestBitcoinWithdrawInvalidAddressName,
diff --git a/e2e/e2etests/e2etests.go b/e2e/e2etests/e2etests.go
index a33737eb41..dd9409e4cf 100644
--- a/e2e/e2etests/e2etests.go
+++ b/e2e/e2etests/e2etests.go
@@ -73,6 +73,7 @@ const (
 	*/
 	TestBitcoinDepositName                = "bitcoin_deposit"
 	TestBitcoinDepositRefundName          = "bitcoin_deposit_refund"
+	TestBitcoinDepositAndCallName         = "bitcoin_deposit_and_call"
 	TestBitcoinWithdrawSegWitName         = "bitcoin_withdraw_segwit"
 	TestBitcoinWithdrawTaprootName        = "bitcoin_withdraw_taproot"
 	TestBitcoinWithdrawMultipleName       = "bitcoin_withdraw_multiple"
@@ -451,6 +452,14 @@ var AllE2ETests = []runner.E2ETest{
 		},
 		TestBitcoinDeposit,
 	),
+	runner.NewE2ETest(
+		TestBitcoinDepositAndCallName,
+		"deposit Bitcoin into ZEVM and call a contract",
+		[]runner.ArgDefinition{
+			{Description: "amount in btc", DefaultValue: "0.001"},
+		},
+		TestBitcoinDepositAndCall,
+	),
 	runner.NewE2ETest(
 		TestBitcoinDepositRefundName,
 		"deposit Bitcoin into ZEVM; expect refund", []runner.ArgDefinition{
diff --git a/e2e/e2etests/test_bitcoin_deposit_call.go b/e2e/e2etests/test_bitcoin_deposit_call.go
new file mode 100644
index 0000000000..0f1fd6dc91
--- /dev/null
+++ b/e2e/e2etests/test_bitcoin_deposit_call.go
@@ -0,0 +1,55 @@
+package e2etests
+
+import (
+	"math/big"
+
+	"github.com/stretchr/testify/require"
+
+	"github.com/zeta-chain/node/e2e/runner"
+	"github.com/zeta-chain/node/e2e/utils"
+	testcontract "github.com/zeta-chain/node/testutil/contracts"
+	crosschaintypes "github.com/zeta-chain/node/x/crosschain/types"
+	zetabitcoin "github.com/zeta-chain/node/zetaclient/chains/bitcoin"
+)
+
+func TestBitcoinDepositAndCall(r *runner.E2ERunner, args []string) {
+	// ARRANGE
+	// Given BTC address
+	r.SetBtcAddress(r.Name, false)
+
+	// Given "Live" BTC network
+	stop := r.MineBlocksIfLocalBitcoin()
+	defer stop()
+
+	// Given amount to send
+	require.Len(r, args, 1)
+	amount := parseFloat(r, args[0])
+	amountTotal := amount + zetabitcoin.DefaultDepositorFee
+
+	// Given a list of UTXOs
+	utxos, err := r.ListDeployerUTXOs()
+	require.NoError(r, err)
+	require.NotEmpty(r, utxos)
+
+	// deploy an example contract in ZEVM
+	contractAddr, _, contract, err := testcontract.DeployExample(r.ZEVMAuth, r.ZEVMClient)
+	require.NoError(r, err)
+	r.Logger.Print("Bitcoin: Example contract deployed at: %s", contractAddr.String())
+
+	// ACT
+	// Send BTC to TSS address with a dummy memo
+	data := []byte("hello satoshi")
+	memo := append(contractAddr.Bytes(), data...)
+	txHash, err := r.SendToTSSFromDeployerWithMemo(amountTotal, utxos, memo)
+	require.NoError(r, err)
+
+	// wait for the cctx to be mined
+	cctx := utils.WaitCctxMinedByInboundHash(r.Ctx, txHash.String(), r.CctxClient, r.Logger, r.CctxTimeout)
+	r.Logger.CCTX(*cctx, "bitcoin_deposit_and_call")
+	utils.RequireCCTXStatus(r, cctx, crosschaintypes.CctxStatus_OutboundMined)
+
+	// check if example contract has been called, 'bar' value should be set to amount
+	amoutSats, err := zetabitcoin.GetSatoshis(amount)
+	require.NoError(r, err)
+	utils.MustHaveCalledExampleContract(r, contract, big.NewInt(amoutSats))
+}
diff --git a/e2e/runner/bitcoin.go b/e2e/runner/bitcoin.go
index f861e8ce8f..10596e7e98 100644
--- a/e2e/runner/bitcoin.go
+++ b/e2e/runner/bitcoin.go
@@ -198,8 +198,11 @@ func (r *E2ERunner) SendToTSSFromDeployerWithMemo(
 		scriptPubkeys[i] = utxo.ScriptPubKey
 	}
 
+	// use static fee 0.0005 BTC to calculate change
 	feeSats := btcutil.Amount(0.0005 * btcutil.SatoshiPerBitcoin)
-	amountSats := btcutil.Amount(amount * btcutil.SatoshiPerBitcoin)
+	amountInt, err := zetabitcoin.GetSatoshis(amount)
+	require.NoError(r, err)
+	amountSats := btcutil.Amount(amountInt)
 	change := inputSats - feeSats - amountSats
 
 	if change < 0 {