diff --git a/drivers/serial/Kconfig.nrfx b/drivers/serial/Kconfig.nrfx
index 3218f461f7ea35..e6f4cbed1f1151 100644
--- a/drivers/serial/Kconfig.nrfx
+++ b/drivers/serial/Kconfig.nrfx
@@ -23,7 +23,7 @@ choice
 
 config UART_0_NRF_UART
 	bool "nRF UART 0"
-	depends on SOC_SERIES_NRF52X || SOC_SERIES_NRF51X
+	depends on HAS_HW_NRF_UART0
 	select NRF_UART_PERIPHERAL
 	help
 	  Enable nRF UART without EasyDMA on port 0.