diff --git a/src/Response.php b/src/Response.php
index 7edab23587..178639ddb5 100644
--- a/src/Response.php
+++ b/src/Response.php
@@ -88,6 +88,16 @@ class Response extends AbstractMessage implements ResponseInterface
     const STATUS_CODE_599 = 599;
     /**#@-*/
 
+    /**
+     * @internal
+     */
+    const MIN_STATUS_CODE_VALUE = 100;
+
+    /**
+     * @internal
+     */
+    const MAX_STATUS_CODE_VALUE = 599;
+
     /**
      * @var array Recommended Reason Phrases
      */
@@ -279,12 +289,16 @@ public function getCookie()
      */
     public function setStatusCode($code)
     {
-        $const = get_class($this) . '::STATUS_CODE_' . $code;
-        if (! is_numeric($code) || ! defined($const)) {
-            $code = is_scalar($code) ? $code : gettype($code);
+        if (! is_numeric($code)
+            || is_float($code)
+            || $code < static::MIN_STATUS_CODE_VALUE
+            || $code > static::MAX_STATUS_CODE_VALUE
+        ) {
             throw new Exception\InvalidArgumentException(sprintf(
-                'Invalid status code provided: "%s"',
-                $code
+                'Invalid status code "%s"; must be an integer between %d and %d, inclusive',
+                is_scalar($code) ? $code : gettype($code),
+                static::MIN_STATUS_CODE_VALUE,
+                static::MAX_STATUS_CODE_VALUE
             ));
         }
 
diff --git a/test/ResponseTest.php b/test/ResponseTest.php
index 6d1f48abef..b62aaa15e4 100644
--- a/test/ResponseTest.php
+++ b/test/ResponseTest.php
@@ -107,12 +107,24 @@ public function testRequestCanSetHeaders()
         $this->assertSame($headers, $response->getHeaders());
     }
 
-    public function testResponseCanSetStatusCode()
+    public function validStatusCode()
+    {
+        for ($i = 100; $i <= 599; ++$i) {
+            yield $i => [$i];
+        }
+    }
+
+    /**
+     * @dataProvider validStatusCode
+     *
+     * @param int $statusCode
+     */
+    public function testResponseCanSetStatusCode($statusCode)
     {
         $response = new Response();
-        $this->assertEquals(200, $response->getStatusCode());
-        $response->setStatusCode('303');
-        $this->assertEquals(303, $response->getStatusCode());
+        $this->assertSame(200, $response->getStatusCode());
+        $response->setStatusCode($statusCode);
+        $this->assertSame($statusCode, $response->getStatusCode());
     }
 
     public function testResponseSetStatusCodeThrowsExceptionOnInvalidCode()
@@ -142,7 +154,7 @@ public function testResponseSetCustomStatusCodeThrowsExceptionOnInvalidCode()
     {
         $response = new Response();
         $this->expectException(InvalidArgumentException::class);
-        $this->expectExceptionMessage('Invalid status code provided: "foo"');
+        $this->expectExceptionMessage('Invalid status code "foo"; must be an integer between 100 and 599, inclusive');
 
         $response->setStatusCode('foo');
     }
@@ -540,8 +552,6 @@ public function testGetVersion()
     public function testUnknownCode()
     {
         $responseStr = $this->readResponse('response_unknown');
-        $this->expectException(InvalidArgumentException::class);
-        $this->expectExceptionMessage('Invalid status code provided: "550"');
         $response = Response::fromString($responseStr);
         $this->assertEquals(550, $response->getStatusCode());
     }