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Design & goals

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Yarden Katz edited this page Jul 4, 2013 · 2 revisions

A simple, fast, purely Pythonic (or Cythonic where needed) implementation of commonly used normalization techniques for RNA-Seq gene expression data, such as:

  • Upper quartile (UQ)
  • Trimmed mean of M-values (TMM)
  • Total counts (TC)
  • LOWESS

Represent experimental design simply for now.

Pythonic implementation of lowess:

https://gist.github.com/agramfort/850437

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