diff --git a/pc/rtp_sender.cc b/pc/rtp_sender.cc
index d8d4b520eb..3ee9145a20 100644
--- a/pc/rtp_sender.cc
+++ b/pc/rtp_sender.cc
@@ -317,8 +317,8 @@ void RtpSenderBase::SetSsrc(uint32_t ssrc) {
       // we need to copy.
       RtpParameters current_parameters =
           media_channel_->GetRtpSendParameters(ssrc_);
-      RTC_DCHECK_GE(current_parameters.encodings.size(),
-                    init_parameters_.encodings.size());
+      RTC_CHECK_GE(current_parameters.encodings.size(),
+                   init_parameters_.encodings.size());
       for (size_t i = 0; i < init_parameters_.encodings.size(); ++i) {
         init_parameters_.encodings[i].ssrc =
             current_parameters.encodings[i].ssrc;
diff --git a/pc/rtp_sender_receiver_unittest.cc b/pc/rtp_sender_receiver_unittest.cc
index 654fffc60d..59d4c606b1 100644
--- a/pc/rtp_sender_receiver_unittest.cc
+++ b/pc/rtp_sender_receiver_unittest.cc
@@ -1151,6 +1151,44 @@ TEST_F(RtpSenderReceiverTest,
   DestroyVideoRtpSender();
 }
 
+#if GTEST_HAS_DEATH_TEST && !defined(WEBRTC_ANDROID)
+using RtpSenderReceiverDeathTest = RtpSenderReceiverTest;
+
+TEST_F(RtpSenderReceiverDeathTest,
+       VideoSenderManualRemoveSimulcastFailsDeathTest) {
+  AddVideoTrack(false);
+
+  std::unique_ptr<MockSetStreamsObserver> set_streams_observer =
+      std::make_unique<MockSetStreamsObserver>();
+  video_rtp_sender_ = VideoRtpSender::Create(worker_thread_, video_track_->id(),
+                                             set_streams_observer.get());
+  ASSERT_TRUE(video_rtp_sender_->SetTrack(video_track_.get()));
+  EXPECT_CALL(*set_streams_observer, OnSetStreams());
+  video_rtp_sender_->SetStreams({local_stream_->id()});
+
+  std::vector<RtpEncodingParameters> init_encodings(2);
+  init_encodings[0].max_bitrate_bps = 60000;
+  init_encodings[1].max_bitrate_bps = 120000;
+  video_rtp_sender_->set_init_send_encodings(init_encodings);
+
+  RtpParameters params = video_rtp_sender_->GetParameters();
+  ASSERT_EQ(2u, params.encodings.size());
+  EXPECT_EQ(params.encodings[0].max_bitrate_bps, 60000);
+
+  // Simulate the setLocalDescription call as if the user used SDP munging
+  // to disable simulcast.
+  std::vector<uint32_t> ssrcs;
+  ssrcs.reserve(2);
+  for (int i = 0; i < 2; ++i)
+    ssrcs.push_back(kVideoSsrcSimulcast + i);
+  cricket::StreamParams stream_params =
+      cricket::StreamParams::CreateLegacy(kVideoSsrc);
+  video_media_channel()->AddSendStream(stream_params);
+  video_rtp_sender_->SetMediaChannel(video_media_channel());
+  EXPECT_DEATH(video_rtp_sender_->SetSsrc(kVideoSsrcSimulcast), "");
+}
+#endif
+
 TEST_F(RtpSenderReceiverTest,
        VideoSenderMustCallGetParametersBeforeSetParametersBeforeNegotiation) {
   video_rtp_sender_ =