diff --git a/python/tvm/script/parser/core/doc.py b/python/tvm/script/parser/core/doc.py
index 5ea83749eadf..1c5241dc8d90 100644
--- a/python/tvm/script/parser/core/doc.py
+++ b/python/tvm/script/parser/core/doc.py
@@ -414,13 +414,20 @@ def subscript_from_doc(x: doc.Subscript) -> ast.Subscript:
                 ctx=from_doc(x.ctx),
             )
         elif isinstance(x.slice, doc.Tuple):
-            result = ast.Subscript(
-                value=from_doc(x.value),
-                slice=ast.ExtSlice(
-                    dims=[from_doc(i) for i in x.slice.elts],
-                ),
-                ctx=from_doc(x.ctx),
-            )
+
+            def remap_dim(doc_item: doc.Expr) -> ast.Expr:
+                ast_item = from_doc(doc_item)
+                if isinstance(ast_item, (ast.Index, ast.Slice)):
+                    return ast_item
+                return ast.Index(value=ast_item)
+
+            # ast.ExtSlice requires a non-empty list of dims, and each dim must be either
+            # a Slice or an Index.
+            if x.slice.elts:
+                ast_slice = ast.ExtSlice(dims=[*map(remap_dim, x.slice.elts)])
+            else:
+                ast_slice = ast.Index(value=ast.Tuple(elts=[], ctx=from_doc(x.ctx)))
+            result = ast.Subscript(value=from_doc(x.value), slice=ast_slice, ctx=from_doc(x.ctx))
         else:
             result = ast.Subscript(
                 value=from_doc(x.value),
diff --git a/tests/python/unittest/test_tvmscript_parser_tir.py b/tests/python/unittest/test_tvmscript_parser_tir.py
index 210c173141c5..ef02df497b7b 100644
--- a/tests/python/unittest/test_tvmscript_parser_tir.py
+++ b/tests/python/unittest/test_tvmscript_parser_tir.py
@@ -292,5 +292,21 @@ def non_starred(a: T.handle, b: T.handle):
     tvm.ir.assert_structural_equal(starred, non_starred)
 
 
+def test_tir_empty_tuple_index():
+    @T.macro
+    def bar(val):
+        T.evaluate(val)
+
+    @T.prim_func(private=True)
+    def func_with_empty_tuple(A: T.Buffer((), "int32"), B: T.Buffer((), "int32")):
+        bar(val=A[()])
+
+    @T.prim_func(private=True)
+    def expected(A: T.Buffer((), "int32"), B: T.Buffer((), "int32")):
+        T.evaluate(A[()])
+
+    tvm.ir.assert_structural_equal(func_with_empty_tuple, expected)
+
+
 if __name__ == "__main__":
     tvm.testing.main()