diff --git a/docs/content-changelog.md b/docs/content-changelog.md index 1a80704..8f3f7f1 100644 --- a/docs/content-changelog.md +++ b/docs/content-changelog.md @@ -5,11 +5,11 @@ The following changes have been made to the content catalogued within the Molecu In addition to the content changes listed below, this release added a therapeutic strategy (`therapy_strategy`) for all sensitive and resistance relationships. Added entries: - -Edited entries: - (FDA) _EGFR_ p.L858R and sensitivity to osimertinib in non-small cell lung cancer. - (FDA) _EGFR_ exon 19 deletions and sensitivity to osimertinib in non-small cell lung cancer. - (FDA) HER2-positive breast cancer and sensitivity to margetuximab-cmkb + chemotherapy. + +Edited entries: - (Guideline) _ABL1_ p.T315I suggesting sensitivity to Omacetaxine in CML has been recategorized from a targeted therapy to chemotherapy. - (Guideline) MSI-High associated with resistance to 5-Fluorouracil in colorectal adenocarcinoma. 5-Fluorouracil was reclassified as a chemotherapy therapy type instead of targeted therapy. - (Guideline) _TET2_ somatic variants suggesting sensitivity to azacitidine was changed from a targeted therapy to chemotherapy.