diff --git a/tests-integration/tests/macros_main.rs b/tests-integration/tests/macros_main.rs
index 31442805141..e34387e5ec1 100644
--- a/tests-integration/tests/macros_main.rs
+++ b/tests-integration/tests/macros_main.rs
@@ -1,4 +1,8 @@
-#![cfg(all(feature = "macros", feature = "rt-multi-thread"))]
+#![cfg(all(
+    feature = "macros",
+    feature = "rt-multi-thread",
+    not(target_os = "wasi")
+))]
 
 #[tokio::main]
 async fn basic_main() -> usize {
diff --git a/tokio-stream/tests/stream_panic.rs b/tokio-stream/tests/stream_panic.rs
index 8ff9ff59b5f..22c1c208001 100644
--- a/tokio-stream/tests/stream_panic.rs
+++ b/tokio-stream/tests/stream_panic.rs
@@ -1,6 +1,5 @@
 #![warn(rust_2018_idioms)]
-#![cfg(feature = "time")]
-#![cfg(not(target_os = "wasi"))] // Wasi does not support panic recovery
+#![cfg(all(feature = "time", not(target_os = "wasi")))] // Wasi does not support panic recovery
 
 use parking_lot::{const_mutex, Mutex};
 use std::error::Error;
diff --git a/tokio/Cargo.toml b/tokio/Cargo.toml
index 5edd9a2f645..b9aa68c8f94 100644
--- a/tokio/Cargo.toml
+++ b/tokio/Cargo.toml
@@ -150,9 +150,11 @@ async-stream = "0.3"
 
 [target.'cfg(not(target_arch = "wasm32"))'.dev-dependencies]
 proptest = "1"
-rand = "0.8.0"
 socket2 = "0.4"
 
+[target.'cfg(not(all(target_arch = "wasm32", target_os = "unknown")))'.dev-dependencies]
+rand = "0.8.0"
+
 [target.'cfg(all(target_arch = "wasm32", not(target_os = "wasi")))'.dev-dependencies]
 wasm-bindgen-test = "0.3.0"
 
diff --git a/tokio/src/io/mod.rs b/tokio/src/io/mod.rs
index cfdda61f694..7113af0c363 100644
--- a/tokio/src/io/mod.rs
+++ b/tokio/src/io/mod.rs
@@ -211,9 +211,11 @@ cfg_io_driver_impl! {
         pub use driver::{Interest, Ready};
     }
 
+    #[cfg_attr(target_os = "wasi", allow(unused_imports))]
     mod poll_evented;
 
     #[cfg(not(loom))]
+    #[cfg_attr(target_os = "wasi", allow(unused_imports))]
     pub(crate) use poll_evented::PollEvented;
 }
 
diff --git a/tokio/src/runtime/blocking/pool.rs b/tokio/src/runtime/blocking/pool.rs
index f73868ee9e7..7dadacc07cf 100644
--- a/tokio/src/runtime/blocking/pool.rs
+++ b/tokio/src/runtime/blocking/pool.rs
@@ -105,6 +105,7 @@ const KEEP_ALIVE: Duration = Duration::from_secs(10);
 /// Tasks will be scheduled as non-mandatory, meaning they may not get executed
 /// in case of runtime shutdown.
 #[track_caller]
+#[cfg_attr(target_os = "wasi", allow(dead_code))]
 pub(crate) fn spawn_blocking<F, R>(func: F) -> JoinHandle<R>
 where
     F: FnOnce() -> R + Send + 'static,
diff --git a/tokio/src/runtime/mod.rs b/tokio/src/runtime/mod.rs
index dad285d1fbd..46a63614e54 100644
--- a/tokio/src/runtime/mod.rs
+++ b/tokio/src/runtime/mod.rs
@@ -204,6 +204,7 @@ cfg_rt! {
 
     mod blocking;
     use blocking::BlockingPool;
+    #[cfg_attr(target_os = "wasi", allow(unused_imports))]
     pub(crate) use blocking::spawn_blocking;
 
     cfg_trace! {
diff --git a/tokio/tests/io_buf_reader.rs b/tokio/tests/io_buf_reader.rs
index 864bc023ab5..0d3f6bafc20 100644
--- a/tokio/tests/io_buf_reader.rs
+++ b/tokio/tests/io_buf_reader.rs
@@ -277,6 +277,7 @@ async fn maybe_pending_buf_read() {
     assert_eq!(v, []);
 }
 
+// https://github.com/rust-lang/futures-rs/pull/1573#discussion_r281162309
 #[tokio::test]
 async fn maybe_pending_seek() {
     struct MaybePendingSeek<'a> {
diff --git a/tokio/tests/rt_basic.rs b/tokio/tests/rt_basic.rs
index c3df1c1a859..73bafdc4d5c 100644
--- a/tokio/tests/rt_basic.rs
+++ b/tokio/tests/rt_basic.rs
@@ -315,6 +315,7 @@ mod unstable {
     }
 
     #[test]
+    #[cfg_attr(target_os = "wasi", ignore = "Wasi does not support panic recovery")]
     fn spawns_do_nothing() {
         use std::sync::Arc;
 
@@ -343,6 +344,7 @@ mod unstable {
     }
 
     #[test]
+    #[cfg_attr(target_os = "wasi", ignore = "Wasi does not support panic recovery")]
     fn shutdown_all_concurrent_block_on() {
         const N: usize = 2;
         use std::sync::{mpsc, Arc};
diff --git a/tokio/tests/rt_metrics.rs b/tokio/tests/rt_metrics.rs
index e86beb91421..3b8070533cf 100644
--- a/tokio/tests/rt_metrics.rs
+++ b/tokio/tests/rt_metrics.rs
@@ -1,5 +1,5 @@
 #![warn(rust_2018_idioms)]
-#![cfg(all(feature = "full", tokio_unstable))]
+#![cfg(all(feature = "full", tokio_unstable, not(target_os = "wasi")))]
 
 use tokio::runtime::Runtime;
 use tokio::time::{self, Duration};
diff --git a/tokio/tests/rt_threaded.rs b/tokio/tests/rt_threaded.rs
index a79007d48bc..187cd557b37 100644
--- a/tokio/tests/rt_threaded.rs
+++ b/tokio/tests/rt_threaded.rs
@@ -1,17 +1,12 @@
 #![warn(rust_2018_idioms)]
-#![cfg(feature = "full")]
+#![cfg(all(feature = "full", not(target_os = "wasi")))]
 
-#[cfg(not(target_os = "wasi"))]
 use tokio::io::{AsyncReadExt, AsyncWriteExt};
-#[cfg(not(target_os = "wasi"))]
 use tokio::net::{TcpListener, TcpStream};
 use tokio::runtime;
 use tokio::sync::oneshot;
-#[cfg(not(target_os = "wasi"))]
-use tokio_test::assert_err;
-use tokio_test::assert_ok;
+use tokio_test::{assert_err, assert_ok};
 
-#[cfg(not(target_os = "wasi"))]
 use futures::future::poll_fn;
 use std::future::Future;
 use std::pin::Pin;
@@ -29,7 +24,6 @@ macro_rules! cfg_metrics {
     }
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn single_thread() {
     // No panic when starting a runtime w/ a single thread
@@ -39,10 +33,6 @@ fn single_thread() {
         .build();
 }
 
-#[cfg_attr(
-    target_os = "wasi",
-    ignore = "WASI: std::mpsc without thread parking not working"
-)]
 #[test]
 fn many_oneshot_futures() {
     // used for notifying the main thread
@@ -170,7 +160,6 @@ fn many_multishot_futures() {
     }
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn spawn_shutdown() {
     let rt = rt();
@@ -190,7 +179,6 @@ fn spawn_shutdown() {
     assert_err!(rx.try_recv());
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support bind
 async fn client_server(tx: mpsc::Sender<()>) {
     let server = assert_ok!(TcpListener::bind("127.0.0.1:0").await);
 
@@ -215,7 +203,6 @@ async fn client_server(tx: mpsc::Sender<()>) {
     tx.send(()).unwrap();
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn drop_threadpool_drops_futures() {
     for _ in 0..1_000 {
@@ -272,7 +259,6 @@ fn drop_threadpool_drops_futures() {
     }
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn start_stop_callbacks_called() {
     use std::sync::atomic::{AtomicUsize, Ordering};
@@ -307,7 +293,6 @@ fn start_stop_callbacks_called() {
     assert!(before_stop.load(Ordering::Relaxed) > 0);
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn blocking() {
     // used for notifying the main thread
@@ -353,7 +338,6 @@ fn blocking() {
     }
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn multi_threadpool() {
     use tokio::sync::oneshot;
@@ -382,7 +366,6 @@ fn multi_threadpool() {
 //
 // The test ensures that, when this happens, attempting to consume from a
 // channel yields occasionally even if there are values ready to receive.
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support threads
 #[test]
 fn coop_and_block_in_place() {
     let rt = tokio::runtime::Builder::new_multi_thread()
@@ -433,7 +416,6 @@ fn coop_and_block_in_place() {
 }
 
 // Testing this does not panic
-#[cfg(not(target_os = "wasi"))] // Wasi does not support threads
 #[test]
 fn max_blocking_threads() {
     let _rt = tokio::runtime::Builder::new_multi_thread()
@@ -442,7 +424,6 @@ fn max_blocking_threads() {
         .unwrap();
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi does not support threads
 #[test]
 #[should_panic]
 fn max_blocking_threads_set_to_zero() {
@@ -452,7 +433,6 @@ fn max_blocking_threads_set_to_zero() {
         .unwrap();
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi does not support threads
 #[tokio::test(flavor = "multi_thread", worker_threads = 2)]
 async fn hang_on_shutdown() {
     let (sync_tx, sync_rx) = std::sync::mpsc::channel::<()>();
@@ -521,19 +501,12 @@ fn wake_during_shutdown() {
         }
     }
 
-    #[cfg(not(target_os = "wasi"))]
     let rt = tokio::runtime::Builder::new_multi_thread()
         .worker_threads(1)
         .enable_all()
         .build()
         .unwrap();
 
-    #[cfg(target_os = "wasi")]
-    let rt = tokio::runtime::Builder::new_current_thread()
-        .enable_all()
-        .build()
-        .unwrap();
-
     let (f1, f2) = MyFuture::new();
 
     rt.spawn(f1);
@@ -542,20 +515,17 @@ fn wake_during_shutdown() {
     rt.block_on(async { tokio::time::sleep(tokio::time::Duration::from_millis(20)).await });
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support panic recovery
 #[should_panic]
 #[tokio::test]
 async fn test_block_in_place1() {
     tokio::task::block_in_place(|| {});
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support panic recovery
 #[tokio::test(flavor = "multi_thread")]
 async fn test_block_in_place2() {
     tokio::task::block_in_place(|| {});
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support panic recovery
 #[should_panic]
 #[tokio::main(flavor = "current_thread")]
 #[test]
@@ -563,20 +533,12 @@ async fn test_block_in_place3() {
     tokio::task::block_in_place(|| {});
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi doesn't support panic recovery
 #[tokio::main]
 #[test]
 async fn test_block_in_place4() {
     tokio::task::block_in_place(|| {});
 }
 
-#[cfg(not(target_os = "wasi"))]
 fn rt() -> runtime::Runtime {
     runtime::Runtime::new().unwrap()
 }
-
-#[cfg(target_os = "wasi")]
-fn rt() -> runtime::Runtime {
-    use runtime::Builder;
-    Builder::new_current_thread().enable_all().build().unwrap()
-}
diff --git a/tokio/tests/sync_mpsc.rs b/tokio/tests/sync_mpsc.rs
index f598db0889a..a1510f57d09 100644
--- a/tokio/tests/sync_mpsc.rs
+++ b/tokio/tests/sync_mpsc.rs
@@ -88,7 +88,7 @@ async fn reserve_disarm() {
 }
 
 #[tokio::test]
-#[cfg(all(feature = "full", not(target_os = "wasi")))]
+#[cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
 async fn send_recv_stream_with_buffer() {
     use tokio_stream::StreamExt;
 
@@ -192,7 +192,7 @@ async fn async_send_recv_unbounded() {
 }
 
 #[tokio::test]
-#[cfg(all(feature = "full", not(target_os = "wasi")))]
+#[cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
 async fn send_recv_stream_unbounded() {
     use tokio_stream::StreamExt;
 
@@ -453,7 +453,7 @@ fn unconsumed_messages_are_dropped() {
 }
 
 #[test]
-#[cfg(all(feature = "full", not(target_os = "wasi")))]
+#[cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
 fn blocking_recv() {
     let (tx, mut rx) = mpsc::channel::<u8>(1);
 
@@ -478,7 +478,7 @@ async fn blocking_recv_async() {
 }
 
 #[test]
-#[cfg(all(feature = "full", not(target_os = "wasi")))]
+#[cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
 fn blocking_send() {
     let (tx, mut rx) = mpsc::channel::<u8>(1);
 
diff --git a/tokio/tests/task_local_set.rs b/tokio/tests/task_local_set.rs
index 91dd998d09c..c2bb4848c56 100644
--- a/tokio/tests/task_local_set.rs
+++ b/tokio/tests/task_local_set.rs
@@ -369,7 +369,10 @@ fn with_timeout(timeout: Duration, f: impl FnOnce() + Send + 'static) {
     thread.join().expect("test thread should not panic!")
 }
 
-#[cfg_attr(target_os = "wasi", ignore = "FIXME: Does not seem to work with WASI")]
+#[cfg_attr(
+    target_os = "wasi",
+    ignore = "`unwrap()` in `with_timeout()` panics on Wasi"
+)]
 #[test]
 fn drop_cancels_remote_tasks() {
     // This test reproduces issue #1885.
@@ -392,7 +395,10 @@ fn drop_cancels_remote_tasks() {
     });
 }
 
-#[cfg(not(target_os = "wasi"))]
+#[cfg_attr(
+    target_os = "wasi",
+    ignore = "FIXME: `task::spawn_local().await.unwrap()` panics on Wasi"
+)]
 #[test]
 fn local_tasks_wake_join_all() {
     // This test reproduces issue #2460.
diff --git a/tokio/tests/test_clock.rs b/tokio/tests/test_clock.rs
index 6141c11b534..891636fdb28 100644
--- a/tokio/tests/test_clock.rs
+++ b/tokio/tests/test_clock.rs
@@ -28,7 +28,6 @@ async fn can_pause_after_resume() {
     assert!(Instant::now() - start < Duration::from_secs(21));
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi does not support panic recovery
 #[tokio::test]
 #[should_panic]
 async fn freezing_time_while_frozen_panics() {
@@ -36,14 +35,12 @@ async fn freezing_time_while_frozen_panics() {
     time::pause();
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi does not support panic recovery
 #[tokio::test]
 #[should_panic]
 async fn advancing_time_when_time_is_not_frozen_panics() {
     time::advance(Duration::from_secs(1)).await;
 }
 
-#[cfg(not(target_os = "wasi"))] // Wasi does not support panic recovery
 #[tokio::test]
 #[should_panic]
 async fn resuming_time_when_not_frozen_panics() {
diff --git a/tokio/tests/time_pause.rs b/tokio/tests/time_pause.rs
index 30b752335b8..6251b4b829f 100644
--- a/tokio/tests/time_pause.rs
+++ b/tokio/tests/time_pause.rs
@@ -1,10 +1,13 @@
 #![warn(rust_2018_idioms)]
-#![cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
+#![cfg(feature = "full")]
 
 use rand::SeedableRng;
 use rand::{rngs::StdRng, Rng};
 use tokio::time::{self, Duration, Instant, Sleep};
-use tokio_test::{assert_elapsed, assert_err, assert_pending, assert_ready, assert_ready_eq, task};
+use tokio_test::{assert_elapsed, assert_pending, assert_ready, assert_ready_eq, task};
+
+#[cfg(not(target_os = "wasi"))]
+use tokio_test::assert_err;
 
 use std::{
     future::Future,
@@ -26,12 +29,14 @@ async fn pause_time_in_task() {
     t.await.unwrap();
 }
 
+#[cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
 #[tokio::test(flavor = "multi_thread", worker_threads = 1)]
 #[should_panic]
 async fn pause_time_in_main_threads() {
     tokio::time::pause();
 }
 
+#[cfg(all(feature = "full", not(target_os = "wasi")))] // Wasi doesn't support threads
 #[tokio::test(flavor = "multi_thread", worker_threads = 1)]
 async fn pause_time_in_spawn_threads() {
     let t = tokio::spawn(async {
diff --git a/tokio/tests/time_timeout.rs b/tokio/tests/time_timeout.rs
index 63ea5c90487..ec871cf62fe 100644
--- a/tokio/tests/time_timeout.rs
+++ b/tokio/tests/time_timeout.rs
@@ -17,7 +17,7 @@ async fn simultaneous_deadline_future_completion() {
     assert_ready_ok!(fut.poll());
 }
 
-#[cfg_attr(target_os = "wasi", ignore = "Wasi does not support threads")]
+#[cfg_attr(target_os = "wasi", ignore = "FIXME: `fut.poll()` panics on Wasi")]
 #[tokio::test]
 async fn completed_future_past_deadline() {
     // Wrap it with a deadline