diff --git a/changelog/224.bugfix.rst b/changelog/224.bugfix.rst
new file mode 100644
index 000000000..18e1f8680
--- /dev/null
+++ b/changelog/224.bugfix.rst
@@ -0,0 +1 @@
+Raises error if NDCube is sliced with an Ellipsis.
diff --git a/ndcube/utils/wcs.py b/ndcube/utils/wcs.py
index 9ea9ebf2a..4a875c3bb 100644
--- a/ndcube/utils/wcs.py
+++ b/ndcube/utils/wcs.py
@@ -184,6 +184,10 @@ def _wcs_slicer(wcs, missing_axes, item):
         new_wcs = wcs.slice(item_checked)
     # if it a tuple like [0:2, 0:3, 2] or [0:2, 1:3]
     elif isinstance(item, tuple):
+        # Ellipsis slicing is currently not supported.
+        # Raise an error if user tries to slice by ellipsis.
+        if Ellipsis in item:
+            raise NotImplementedError("Slicing FITS-WCS by ellipsis not supported.")
         # this is used to not exceed the range of the item tuple
         # if the check of the missing_axes which is False if not dead
         # is a success than the the item of the tuple is added one by