diff --git a/ndcube/utils/wcs.py b/ndcube/utils/wcs.py
index 981b8ca0c..a9384bbf3 100644
--- a/ndcube/utils/wcs.py
+++ b/ndcube/utils/wcs.py
@@ -183,6 +183,10 @@ def _wcs_slicer(wcs, missing_axes, item):
         new_wcs = wcs.slice(item_checked)
     # if it a tuple like [0:2, 0:3, 2] or [0:2, 1:3]
     elif isinstance(item, tuple):
+        # Ellipsis slicing is currently not supported.
+        # Raise an error if user tries to slice by ellipsis.
+        if type(Ellipsis) in [type(item_i) for item_i in item]:
+            raise NotImplementedError("Slicing FITS-WCS by ellipsis not supported.")
         # this is used to not exceed the range of the item tuple
         # if the check of the missing_axes which is False if not dead
         # is a success than the the item of the tuple is added one by