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Quarto GHA Workflow Runner committed Jun 21, 2024
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2 changes: 1 addition & 1 deletion .nojekyll
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13 changes: 6 additions & 7 deletions index.html
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Expand Up @@ -179,7 +179,6 @@ <h2 id="toc-title">On this page</h2>
<li><a href="#what-has-changed-since" id="toc-what-has-changed-since" class="nav-link" data-scroll-target="#what-has-changed-since">What has changed since?</a></li>
</ul></li>
<li><a href="#what-will-dp-next-do" id="toc-what-will-dp-next-do" class="nav-link" data-scroll-target="#what-will-dp-next-do">What will DP-Next do?</a></li>
<li><a href="#who-are-we" id="toc-who-are-we" class="nav-link" data-scroll-target="#who-are-we">Who are we?</a></li>
</ul>
<div class="toc-actions"><ul><li><a href="https://github.com/steno-aarhus/dp-next/edit/main/index.qmd" class="toc-action"><i class="bi bi-github"></i>Edit this page</a></li><li><a href="https://github.com/steno-aarhus/dp-next/issues/new" class="toc-action"><i class="bi empty"></i>Report an issue</a></li><li><a href="https://github.com/steno-aarhus/dp-next/blob/main/index.qmd" class="toc-action"><i class="bi empty"></i>View source</a></li></ul></div></nav>
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Expand Down Expand Up @@ -247,12 +246,12 @@ <h2 class="anchored" data-anchor-id="what-will-dp-next-do">What will DP-Next do?
</figcaption>
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<p>WP1 (Management and Collaboration) will manage the project and foster deep collaboration between all partners. WP2 (Risk Prediction) will develop an exclusively register-based diabetes risk prediction model for the entire Danish, Greenlandic and Faroese populations, applying advanced statistical and machine learning approaches on a wide set of risk indicators. It will map out meaningful subgroups and validate internally and in external populations. WP3 (Heterogeneity) will map out heterogeneity in T2D risk in a subgroup of ~1000 participants with HbA1c-based pre-diabetes with a special focus on regional fat distribution, hepatic steatosis and insulin resistance. WP4 (Intervention Development) will develop an intervention for sustainable primary diabetes prevention based on co-creation, a systems approach and the “Complex Interventions” framework and evaluate the pragmatic feasibility of intervention components in two risk subgroups in real life practical settings.</p>
<p>See the WP tabs for more details about each Work Packages</p>
</section>
<section id="who-are-we" class="level2">
<h2 class="anchored" data-anchor-id="who-are-we">Who are we?</h2>
<p>DP-Next will be carried out by a cross disciplinary team of epidemiologists, clinicians, health scientists and data scientists across all seven Steno Diabetes Centres.</p>
<ul>
<li>WP1 (Management and Collaboration) will manage the project and foster deep collaboration between all partners.</li>
<li>WP2 (Risk Prediction) will develop an exclusively register-based diabetes risk prediction model for the entire Danish, Greenlandic and Faroese populations, applying advanced statistical and machine learning approaches on a wide set of risk indicators. It will map out meaningful subgroups and validate internally and in external populations.</li>
<li>WP3 (Heterogeneity) will map out heterogeneity in T2D risk in a new deeply phenotyped cohort of 1000 participants with HbA1c-based pre-diabetes with a core protocol focused on regional fat distribution, hepatic steatosis, beta cell function and insulin resistance plus the creation of an extensive biobank and the ambition for an extended protocol.</li>
<li>WP4 (Intervention Development) will develop an intervention for sustainable primary diabetes prevention based on co-creation, a “Participatory System Dynamics Approach” and the “Complex Interventions” framework and evaluate the pragmatic feasibility of intervention components in specific risk subgroups in real life practical settings.</li>
</ul>


</section>
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"text": "What will DP-Next do?\nWe aim to use these developments to design and deliver a sustainably effective strategy for prevention of T2D in Denmark, Greenland and the Faroe Islands.\nWe will work towards this aim in four Work Packages (WP) across all seven Steno Diabetes Centres:\n\n\n\n\n\n\nFigure 1: There are 5 Steno Diabetes Centers in Denmark, one in Greenland and one on the Faroe Islands.\n\n\n\nWP1 (Management and Collaboration) will manage the project and foster deep collaboration between all partners. WP2 (Risk Prediction) will develop an exclusively register-based diabetes risk prediction model for the entire Danish, Greenlandic and Faroese populations, applying advanced statistical and machine learning approaches on a wide set of risk indicators. It will map out meaningful subgroups and validate internally and in external populations. WP3 (Heterogeneity) will map out heterogeneity in T2D risk in a subgroup of ~1000 participants with HbA1c-based pre-diabetes with a special focus on regional fat distribution, hepatic steatosis and insulin resistance. WP4 (Intervention Development) will develop an intervention for sustainable primary diabetes prevention based on co-creation, a systems approach and the “Complex Interventions” framework and evaluate the pragmatic feasibility of intervention components in two risk subgroups in real life practical settings.\nSee the WP tabs for more details about each Work Packages"
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"text": "What will DP-Next do?\nWe aim to use these developments to design and deliver a sustainably effective strategy for prevention of T2D in Denmark, Greenland and the Faroe Islands.\nWe will work towards this aim in four Work Packages (WP) across all seven Steno Diabetes Centres:\n\n\n\n\n\n\nFigure 1: There are 5 Steno Diabetes Centers in Denmark, one in Greenland and one on the Faroe Islands.\n\n\n\n\nWP1 (Management and Collaboration) will manage the project and foster deep collaboration between all partners.\nWP2 (Risk Prediction) will develop an exclusively register-based diabetes risk prediction model for the entire Danish, Greenlandic and Faroese populations, applying advanced statistical and machine learning approaches on a wide set of risk indicators. It will map out meaningful subgroups and validate internally and in external populations.\nWP3 (Heterogeneity) will map out heterogeneity in T2D risk in a new deeply phenotyped cohort of 1000 participants with HbA1c-based pre-diabetes with a core protocol focused on regional fat distribution, hepatic steatosis, beta cell function and insulin resistance plus the creation of an extensive biobank and the ambition for an extended protocol.\nWP4 (Intervention Development) will develop an intervention for sustainable primary diabetes prevention based on co-creation, a “Participatory System Dynamics Approach” and the “Complex Interventions” framework and evaluate the pragmatic feasibility of intervention components in specific risk subgroups in real life practical settings."
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