DESCRIPTION

Package: scHOT
Type: Package
Title: single-cell higher order testing
Version: 0.99.7
Authors@R: c(
    person("Shila", "Ghazanfar", email = "shazanfar@gmail.com", role = c("aut", "cre")
    ),
    person("Yingxin", "Lin", email = "yingxin.lin@sydney.edu.au", role = c("aut")
    ))
Description: Single cell Higher Order Testing (scHOT) is an R package that facilitates testing changes in higher order structure of gene expression along either a developmental trajectory or across space. scHOT is general and modular in nature, can be run in multiple data contexts such as along a continuous trajectory, between discrete groups, and over spatial orientations; as well as accommodate any higher order measurement such as variability or correlation. scHOT meaningfully adds to first order effect testing, such as differential expression, and provides a framework for interrogating higher order interactions from single cell data.
License: GPL-3
Encoding: UTF-8
LazyData: true
Depends: R (>= 4.0)
Imports:
    S4Vectors (>= 0.24.3),
    SingleCellExperiment,
    Matrix,
    SummarizedExperiment,
    IRanges,
    methods,
    stats,
    BiocParallel,
    reshape,
    ggplot2,
    igraph,
    grDevices,
    ggforce,
    graphics
RoxygenNote: 7.2.1
Suggests: knitr, rmarkdown, scater, scattermore, scales, matrixStats, deldir
VignetteBuilder: knitr
biocViews: GeneExpression, RNASeq, Sequencing, SingleCell, Software, Transcriptomics