diff --git a/CHANGELOG.md b/CHANGELOG.md
index b3816eec83..d9d665815c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -47,6 +47,7 @@ For upgrade instructions, please check the [migration guide](MIGRATIONS.md).
 - Added a button to the users list view that revokes admin rights from all selected users. [#3378](https://github.com/scalableminds/webknossos/pull/3378)
 - Hybrid tracings are now enabled by default. They allow to combine the functionality of skeleton and volume annotations in one tracing. [#3399](https://github.com/scalableminds/webknossos/pull/3399)
 - A User can now have multiple layouts for tracing views. [#3299](https://github.com/scalableminds/webknossos/pull/3299)
+- Added support for datasets with sparse resolutions (e.g., [[1, 1, 1], [16, 16, 16]]). [#3406](https://github.com/scalableminds/webknossos/pull/3406)
 - The info tab in tracing views now displays the extent of the current dataset. [#3371](https://github.com/scalableminds/webknossos/pull/3371).
 
 ### Changed
diff --git a/app/assets/javascripts/oxalis/model_initialization.js b/app/assets/javascripts/oxalis/model_initialization.js
index 5fa437e6e2..2d429f7876 100644
--- a/app/assets/javascripts/oxalis/model_initialization.js
+++ b/app/assets/javascripts/oxalis/model_initialization.js
@@ -27,6 +27,7 @@ import * as Utils from "libs/utils";
 import DataLayer from "oxalis/model/data_layer";
 import ConnectionInfo from "oxalis/model/data_connection_info";
 import { ControlModeEnum } from "oxalis/constants";
+import type { Vector3 } from "oxalis/constants";
 import Toast from "libs/toast";
 import ErrorHandling from "libs/error_handling";
 import UrlManager from "oxalis/controller/url_manager";
@@ -252,9 +253,38 @@ function initializeDataset(
     dataset.dataSource.dataLayers = newDataLayers;
   });
 
+  ensureDenseLayerResolutions(dataset);
   Store.dispatch(setDatasetAction(dataset));
 }
 
+function ensureDenseLayerResolutions(dataset: APIDataset) {
+  for (const layer of dataset.dataSource.dataLayers) {
+    layer.resolutions = convertToDenseResolution(layer.resolutions);
+  }
+}
+
+function convertToDenseResolution(resolutions: Array<Vector3>) {
+  // Each resolution entry can be characterized by it's greatest resolution dimension.
+  // E.g., the resolution array [[1, 1, 1], [2, 2, 1], [4, 4, 2]] defines that
+  // a log zoomstep of 2 corresponds to the resolution [2, 2, 1] (and not [4, 4, 2]).
+  // Therefore, the largest dim for each resolution has to be unique across all resolutions.
+
+  // This function returns an array of resolutions, for which each index will
+  // hold a resolution with highest_dim === 2**index.
+
+  if (resolutions.length !== _.uniqBy(resolutions.map(_.max)).length) {
+    throw new Error("Max dimension in resolutions is not unique.");
+  }
+  const paddedResolutionCount = 1 + Math.log2(_.max(resolutions.map(v => _.max(v))));
+  const resolutionsLookUp = _.keyBy(resolutions, _.max);
+
+  return _.range(0, paddedResolutionCount).map(exp => {
+    const resPower = 2 ** exp;
+    // If the resolution does not exist, use a fallback resolution
+    return resolutionsLookUp[resPower] || [resPower, resPower, resPower];
+  });
+}
+
 function initializeSettings(initialUserSettings: Object, initialDatasetSettings: Object): void {
   Store.dispatch(initializeSettingsAction(initialUserSettings, initialDatasetSettings));
 }
diff --git a/flow-typed/npm/lodash_v4.x.x.js b/flow-typed/npm/lodash_v4.x.x.js
index 79f573f4b9..ba249e7285 100644
--- a/flow-typed/npm/lodash_v4.x.x.js
+++ b/flow-typed/npm/lodash_v4.x.x.js
@@ -472,6 +472,7 @@ declare module "lodash" {
     divide(dividend: number, divisor: number): number;
     floor(number: number, precision?: number): number;
     max<T>(array: ?Array<T>): T;
+    max<T>(array: [T, T, T]): T;
     maxBy<T>(array: ?Array<T>, iteratee?: Iteratee<T>): T;
     mean(array: Array<*>): number;
     meanBy<T>(array: Array<T>, iteratee?: Iteratee<T>): number;