diff --git a/htscodecs/rANS_static32x16pr.h b/htscodecs/rANS_static32x16pr.h
index 0ca1c32..0aa2dcd 100644
--- a/htscodecs/rANS_static32x16pr.h
+++ b/htscodecs/rANS_static32x16pr.h
@@ -146,7 +146,7 @@ unsigned char *rans_uncompress_O1_32x16_avx512(unsigned char *in,
 
 //----------------------------------------------------------------------
 // Arm Neon implementation
-#ifdef __ARM_NEON
+#if defined(__ARM_NEON) && defined(__aarch64__)
 unsigned char *rans_compress_O0_32x16_neon(unsigned char *in,
                                            unsigned int in_size,
                                            unsigned char *out,
diff --git a/htscodecs/rANS_static32x16pr_neon.c b/htscodecs/rANS_static32x16pr_neon.c
index e5312da..bb6b268 100644
--- a/htscodecs/rANS_static32x16pr_neon.c
+++ b/htscodecs/rANS_static32x16pr_neon.c
@@ -32,7 +32,7 @@
  */
 
 #include "config.h"
-#ifdef __ARM_NEON
+#if defined(__ARM_NEON) && defined(__aarch64__)
 #include <arm_neon.h>
 
 #include <limits.h>
diff --git a/htscodecs/rANS_static4x16pr.c b/htscodecs/rANS_static4x16pr.c
index b6d5580..c16edda 100644
--- a/htscodecs/rANS_static4x16pr.c
+++ b/htscodecs/rANS_static4x16pr.c
@@ -1006,7 +1006,7 @@ unsigned char *(*rans_dec_func(int do_simd, int order))
     }
 }
 
-#elif defined(__ARM_NEON)
+#elif defined(__ARM_NEON) && defined(__aarch64__)
 
 #if defined(__linux__) || defined(__FreeBSD__)
 #include <sys/auxv.h>