diff --git a/src/components/Select.vue b/src/components/Select.vue
index c3ade5e7e..ab4b9a70b 100644
--- a/src/components/Select.vue
+++ b/src/components/Select.vue
@@ -1039,11 +1039,13 @@
               'aria-autocomplete': 'list',
               'aria-labelledby': `vs${this.uid}__combobox`,
               'aria-controls': `vs${this.uid}__listbox`,
-              'aria-activedescendant': this.typeAheadPointer > -1 ? `vs${this.uid}__option-${this.typeAheadPointer}` : '',
               'ref': 'search',
               'type': 'search',
               'autocomplete': this.autocomplete,
               'value': this.search,
+              ...(this.dropdownOpen && this.filteredOptions[this.typeAheadPointer] ? {
+                'aria-activedescendant': `vs${this.uid}__option-${this.typeAheadPointer}`
+              } : {}),
             },
             events: {
               'compositionstart': () => this.isComposing = true,
diff --git a/tests/unit/Accessibility.spec.js b/tests/unit/Accessibility.spec.js
new file mode 100644
index 000000000..793b76e43
--- /dev/null
+++ b/tests/unit/Accessibility.spec.js
@@ -0,0 +1,35 @@
+import { mountDefault } from "../helpers";
+
+describe("Search Slot Scope", () => {
+  /**
+   * @see https://www.w3.org/WAI/PF/aria/states_and_properties#aria-activedescendant
+   */
+  describe("aria-activedescendant", () => {
+    it("adds the active descendant attribute only when the dropdown is open and there is a typeAheadPointer value", async () => {
+      const Select = mountDefault();
+
+      expect(
+        Select.vm.scope.search.attributes["aria-activedescendant"]
+      ).toEqual(undefined);
+
+      Select.vm.open = true;
+      await Select.vm.$nextTick();
+
+      expect(
+        Select.vm.scope.search.attributes["aria-activedescendant"]
+      ).toEqual(undefined);
+    });
+
+    it("adds the active descendant attribute when there's a typeahead value and an open dropdown", async () => {
+      const Select = mountDefault();
+
+      Select.vm.open = true;
+      Select.vm.typeAheadPointer = 1;
+      await Select.vm.$nextTick();
+
+      expect(
+        Select.vm.scope.search.attributes["aria-activedescendant"]
+      ).toEqual(`vs${Select.vm.uid}__option-1`);
+    });
+  });
+});