diff --git a/build.rs b/build.rs
index 78ed993441d53..15bf2f5a8cb16 100644
--- a/build.rs
+++ b/build.rs
@@ -18,7 +18,6 @@ const ALLOWED_CFGS: &'static [&'static str] = &[
     "libc_const_extern_fn_unstable",
     "libc_deny_warnings",
     "libc_long_array",
-    "libc_ptr_addr_of",
     "libc_thread_local",
     "libc_underscore_const_names",
     "libc_ctest",
@@ -87,10 +86,6 @@ fn main() {
         set_cfg("libc_long_array");
     }
 
-    if rustc_minor_ver >= 51 || rustc_dep_of_std {
-        set_cfg("libc_ptr_addr_of");
-    }
-
     // Rust >= 1.37.0 allows underscores as anonymous constant names.
     if rustc_minor_ver >= 37 || rustc_dep_of_std {
         set_cfg("libc_underscore_const_names");
diff --git a/src/macros.rs b/src/macros.rs
index 6d728d078d85f..cb77cc6c2e822 100644
--- a/src/macros.rs
+++ b/src/macros.rs
@@ -311,17 +311,3 @@ macro_rules! deprecated_mach {
         )*
     }
 }
-
-#[cfg(not(libc_ptr_addr_of))]
-macro_rules! ptr_addr_of {
-    ($place:expr) => {
-        &$place
-    };
-}
-
-#[cfg(libc_ptr_addr_of)]
-macro_rules! ptr_addr_of {
-    ($place:expr) => {
-        ::core::ptr::addr_of!($place)
-    };
-}
diff --git a/src/wasi/mod.rs b/src/wasi/mod.rs
index b157ab0d59b04..980cda9740ea4 100644
--- a/src/wasi/mod.rs
+++ b/src/wasi/mod.rs
@@ -380,16 +380,16 @@ cfg_if! {
         // `addr_of!(EXTERN_STATIC)` is now safe; remove `unsafe` when MSRV >= 1.82
         #[allow(unused_unsafe)]
         pub static CLOCK_MONOTONIC: clockid_t =
-            unsafe { clockid_t(ptr_addr_of!(_CLOCK_MONOTONIC)) };
+            clockid_t(core::ptr::addr_of!(_CLOCK_MONOTONIC));
         #[allow(unused_unsafe)]
         pub static CLOCK_PROCESS_CPUTIME_ID: clockid_t =
-            unsafe { clockid_t(ptr_addr_of!(_CLOCK_PROCESS_CPUTIME_ID)) };
+            clockid_t(core::ptr::addr_of!(_CLOCK_PROCESS_CPUTIME_ID));
         #[allow(unused_unsafe)]
         pub static CLOCK_REALTIME: clockid_t =
-            unsafe { clockid_t(ptr_addr_of!(_CLOCK_REALTIME)) };
+            clockid_t(core::ptr::addr_of!(_CLOCK_REALTIME));
         #[allow(unused_unsafe)]
         pub static CLOCK_THREAD_CPUTIME_ID: clockid_t =
-            unsafe { clockid_t(ptr_addr_of!(_CLOCK_THREAD_CPUTIME_ID)) };
+            clockid_t(core::ptr::addr_of!(_CLOCK_THREAD_CPUTIME_ID));
     }
 }