diff --git a/lib/action_controller/serialization.rb b/lib/action_controller/serialization.rb
index 11c70fe6d..6fcb5df75 100644
--- a/lib/action_controller/serialization.rb
+++ b/lib/action_controller/serialization.rb
@@ -53,6 +53,14 @@ def use_adapter?
       end
     end
 
+    def rescue_with_handler(exception)
+      @_serializer = nil
+      @_serializer_opts = nil
+      @_adapter_opts = nil
+
+      super(exception)
+    end
+
     module ClassMethods
       def serialization_scope(scope)
         self._serialization_scope = scope
diff --git a/test/action_controller/rescue_from_test.rb b/test/action_controller/rescue_from_test.rb
new file mode 100644
index 000000000..d52ea8e67
--- /dev/null
+++ b/test/action_controller/rescue_from_test.rb
@@ -0,0 +1,32 @@
+require 'test_helper'
+
+module ActionController
+  module Serialization
+    class RescueFromTest < ActionController::TestCase
+      class MyController < ActionController::Base
+        rescue_from Exception, with: :handle_error
+
+        def render_using_raise_error_serializer
+          @profile = Profile.new({ name: 'Name 1', description: 'Description 1', comments: 'Comments 1' })
+          render json: [@profile], serializer: RaiseErrorSerializer
+        end
+
+        def handle_error(exception)
+          render json: { errors: ['Internal Server Error'] }, status: :internal_server_error
+        end
+      end
+
+      tests MyController
+
+      def test_rescue_from
+        get :render_using_raise_error_serializer
+
+        expected = {
+          errors: ['Internal Server Error']
+        }.to_json
+
+        assert_equal expected, @response.body
+      end
+    end
+  end
+end
diff --git a/test/fixtures/poro.rb b/test/fixtures/poro.rb
index 69185394f..8fca91d69 100644
--- a/test/fixtures/poro.rb
+++ b/test/fixtures/poro.rb
@@ -211,3 +211,9 @@ def self.root_name
 Spam::UnrelatedLinkSerializer = Class.new(ActiveModel::Serializer) do
   attributes :id
 end
+
+RaiseErrorSerializer = Class.new(ActiveModel::Serializer) do
+  def json_key
+    raise StandardError, 'Intentional error for rescue_from test'
+  end
+end