diff --git a/Dockerfile b/Dockerfile
index 7067f11..4cfa6ba 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,13 +1,13 @@
-FROM amazonlinux:2018.03
+FROM amazonlinux:2
 
 # Need to set "ulimit -n" to a small value to stop yum from hanging:
 # https://bugzilla.redhat.com/show_bug.cgi?id=1715254#c1
 RUN ulimit -n 1024 && yum -y update && yum -y install \
 	git \
 	gcc \
-	python36 \
-	python36-pip \
-	python36-devel \
+	python38 \
+	python38-pip \
+	python38-devel \
 	jq \
 	nano \
 	unzip \
@@ -16,7 +16,7 @@ RUN ulimit -n 1024 && yum -y update && yum -y install \
 
 COPY requirements.txt quilt/requirements.txt
 
-RUN python3 -m pip install pip==18.1
+RUN python3 -m pip install pip==21.1.1
 
 # Requirements copied from lambda Python 3.6, but not in base image
 # (Plus Cython which is a build-time requirement for numpy)
diff --git a/requirements.txt b/requirements.txt
index a709c7a..8d28e83 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,10 +1,11 @@
-# from `pip freeze` under Python 3.6 lambda image 16-Apr-2020
-boto3==1.12.22
-botocore==1.15.22
-Cython==0.29.21
-docutils==0.15.2
-jmespath==0.9.5
-python-dateutil==2.8.1
-s3transfer==0.3.3
-six==1.14.0
-urllib3==1.25.8
+# from `pip freeze` under Python 3.8 lambda image 01-Sep-2021
+boto3==1.17.100
+botocore==1.20.100
+Cython==0.29.24
+jmespath==0.10.0
+python-dateutil==2.8.2
+rapid-client==0.0.0
+s3transfer==0.4.2
+six==1.16.0
+urllib3==1.26.6
+