diff --git a/integration-tests/rest-client-reactive/pom.xml b/integration-tests/rest-client-reactive/pom.xml
index 318f28d271932..55c61d25554a1 100644
--- a/integration-tests/rest-client-reactive/pom.xml
+++ b/integration-tests/rest-client-reactive/pom.xml
@@ -74,6 +74,11 @@
             <artifactId>quarkus-junit5-mockito</artifactId>
             <scope>test</scope>
         </dependency>
+        <dependency>
+            <groupId>io.quarkus</groupId>
+            <artifactId>quarkus-test-vertx</artifactId>
+            <scope>test</scope>
+        </dependency>
         <dependency>
             <groupId>com.github.tomakehurst</groupId>
             <artifactId>wiremock-jre8-standalone</artifactId>
diff --git a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java
index 104871aa1ef07..950fe0ea3b9cf 100644
--- a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java
+++ b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/ClientCallingResource.java
@@ -74,6 +74,10 @@ void init(@Observes Router router) {
             rc.response().end("Hello World!");
         });
 
+        router.get("/correlation").handler(rc -> {
+            rc.response().end(rc.request().getHeader(CorrelationIdClient.CORRELATION_ID_HEADER_NAME));
+        });
+
         router.post("/call-client-with-global-client-logger").blockingHandler(rc -> {
             String url = rc.body().asString();
             ClientWithClientLogger client = QuarkusRestClientBuilder.newBuilder().baseUri(URI.create(url))
diff --git a/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/CorrelationIdClient.java b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/CorrelationIdClient.java
new file mode 100644
index 0000000000000..213fdf4234d04
--- /dev/null
+++ b/integration-tests/rest-client-reactive/src/main/java/io/quarkus/it/rest/client/main/CorrelationIdClient.java
@@ -0,0 +1,31 @@
+package io.quarkus.it.rest.client.main;
+
+import jakarta.ws.rs.GET;
+import jakarta.ws.rs.Path;
+import jakarta.ws.rs.client.ClientRequestContext;
+import jakarta.ws.rs.client.ClientRequestFilter;
+
+import org.eclipse.microprofile.rest.client.annotation.RegisterProvider;
+import org.eclipse.microprofile.rest.client.inject.RegisterRestClient;
+
+import io.smallrye.common.vertx.ContextLocals;
+
+@Path("/correlation")
+@RegisterRestClient(configKey = "correlation")
+@RegisterProvider(CorrelationIdClient.CorrelationIdClientFilter.class)
+public interface CorrelationIdClient {
+
+    String CORRELATION_ID_HEADER_NAME = "CorrelationId";
+
+    @GET
+    String get();
+
+    class CorrelationIdClientFilter implements ClientRequestFilter {
+
+        @Override
+        public void filter(ClientRequestContext requestContext) {
+            String correlationId = ContextLocals.<String> get(CORRELATION_ID_HEADER_NAME).orElse(null);
+            requestContext.getHeaders().putSingle(CORRELATION_ID_HEADER_NAME, correlationId);
+        }
+    }
+}
diff --git a/integration-tests/rest-client-reactive/src/main/resources/application.properties b/integration-tests/rest-client-reactive/src/main/resources/application.properties
index 5a438ed680a25..e76e85e297bd1 100644
--- a/integration-tests/rest-client-reactive/src/main/resources/application.properties
+++ b/integration-tests/rest-client-reactive/src/main/resources/application.properties
@@ -1,8 +1,8 @@
 w-client-logger/mp-rest/url=${test.url}
 w-exception-mapper/mp-rest/url=${test.url}
 w-fault-tolerance/mp-rest/url=${test.url}
+correlation/mp-rest/url=${test.url}
 io.quarkus.it.rest.client.main.ParamClient/mp-rest/url=${test.url}
-io.quarkus.it.rest.client.multipart.MultipartClient/mp-rest/url=${test.url}
 # global client logging scope
 quarkus.rest-client.logging.scope=request-response
 # Self-Signed client
diff --git a/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/RestClientInTestMethodWithContextTest.java b/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/RestClientInTestMethodWithContextTest.java
new file mode 100644
index 0000000000000..579fa1e432a29
--- /dev/null
+++ b/integration-tests/rest-client-reactive/src/test/java/io/quarkus/it/rest/client/RestClientInTestMethodWithContextTest.java
@@ -0,0 +1,25 @@
+package io.quarkus.it.rest.client;
+
+import static org.assertj.core.api.Assertions.assertThat;
+
+import org.eclipse.microprofile.rest.client.inject.RestClient;
+import org.junit.jupiter.api.Test;
+
+import io.quarkus.it.rest.client.main.CorrelationIdClient;
+import io.quarkus.test.junit.QuarkusTest;
+import io.quarkus.test.vertx.RunOnVertxContext;
+import io.smallrye.common.vertx.ContextLocals;
+
+@QuarkusTest
+public class RestClientInTestMethodWithContextTest {
+
+    @RestClient
+    CorrelationIdClient client;
+
+    @RunOnVertxContext(runOnEventLoop = false)
+    @Test
+    public void test() {
+        ContextLocals.put(CorrelationIdClient.CORRELATION_ID_HEADER_NAME, "dummy");
+        assertThat(client.get()).isEqualTo("dummy");
+    }
+}
diff --git a/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContext.java b/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContext.java
index 13e35c64e8f65..271c9202357bd 100644
--- a/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContext.java
+++ b/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContext.java
@@ -32,4 +32,9 @@
      * @return {@code true} by default.
      */
     boolean duplicateContext() default true;
+
+    /**
+     * If {@code true}, the test method is run on the Event Loop, otherwise it will be run on Vert.x blocking thread pool
+     */
+    boolean runOnEventLoop() default true;
 }
diff --git a/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContextTestMethodInvoker.java b/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContextTestMethodInvoker.java
index 39214de3f94b3..30c027f212135 100644
--- a/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContextTestMethodInvoker.java
+++ b/test-framework/vertx/src/main/java/io/quarkus/test/vertx/RunOnVertxContextTestMethodInvoker.java
@@ -16,6 +16,7 @@
 import io.smallrye.common.vertx.VertxContext;
 import io.vertx.core.Context;
 import io.vertx.core.Handler;
+import io.vertx.core.Promise;
 import io.vertx.core.Vertx;
 
 public class RunOnVertxContextTestMethodInvoker implements TestMethodInvoker {
@@ -70,17 +71,27 @@ public Object invoke(Object actualTestInstance, Method actualTestMethod, List<Ob
             throw new IllegalStateException("Vert.x instance has not been created before attempting to run test method '"
                     + actualTestMethod.getName() + "' of test class '" + testClassName + "'");
         }
-        CompletableFuture<Object> cf = new CompletableFuture<>();
-        RunTestMethodOnContextHandler handler = new RunTestMethodOnContextHandler(actualTestInstance, actualTestMethod,
-                actualTestMethodArgs, uniAsserter, cf);
+
         Context context = vertx.getOrCreateContext();
-        boolean shouldDuplicateContext = shouldContextBeDuplicated(
-                actualTestInstance != null ? actualTestInstance.getClass() : Object.class, actualTestMethod);
+        Class<?> testClass = actualTestInstance != null ? actualTestInstance.getClass() : Object.class;
+        boolean shouldDuplicateContext = shouldContextBeDuplicated(testClass, actualTestMethod);
         if (shouldDuplicateContext) {
             context = VertxContext.getOrCreateDuplicatedContext(context);
             VertxContextSafetyToggle.setContextSafe(context, true);
         }
-        context.runOnContext(handler);
+
+        CompletableFuture<Object> cf;
+        if (shouldRunOnEventLoop(testClass, actualTestMethod)) {
+            cf = new CompletableFuture<>();
+            var handler = new RunTestMethodOnVertxEventLoopContextHandler(actualTestInstance, actualTestMethod,
+                    actualTestMethodArgs, uniAsserter, cf);
+            context.runOnContext(handler);
+        } else {
+            var handler = new RunTestMethodOnVertxBlockingContextHandler(actualTestInstance, actualTestMethod,
+                    actualTestMethodArgs, uniAsserter);
+            cf = ((CompletableFuture) context.executeBlocking(handler).toCompletionStage());
+        }
+
         try {
             return cf.get();
         } catch (InterruptedException e) {
@@ -90,6 +101,7 @@ public Object invoke(Object actualTestInstance, Method actualTestMethod, List<Ob
             // the test itself threw an exception
             throw e.getCause();
         }
+
     }
 
     private boolean shouldContextBeDuplicated(Class<?> c, Method m) {
@@ -106,7 +118,19 @@ private boolean shouldContextBeDuplicated(Class<?> c, Method m) {
         }
     }
 
-    public static class RunTestMethodOnContextHandler implements Handler<Void> {
+    private boolean shouldRunOnEventLoop(Class<?> c, Method m) {
+        RunOnVertxContext runOnVertxContext = m.getAnnotation(RunOnVertxContext.class);
+        if (runOnVertxContext == null) {
+            runOnVertxContext = c.getAnnotation(RunOnVertxContext.class);
+        }
+        if (runOnVertxContext == null) {
+            return true;
+        } else {
+            return runOnVertxContext.runOnEventLoop();
+        }
+    }
+
+    public static class RunTestMethodOnVertxEventLoopContextHandler implements Handler<Void> {
         private static final Runnable DO_NOTHING = new Runnable() {
             @Override
             public void run() {
@@ -119,7 +143,7 @@ public void run() {
         private final DefaultUniAsserter uniAsserter;
         private final CompletableFuture<Object> future;
 
-        public RunTestMethodOnContextHandler(Object testInstance, Method targetMethod, List<Object> methodArgs,
+        public RunTestMethodOnVertxEventLoopContextHandler(Object testInstance, Method targetMethod, List<Object> methodArgs,
                 DefaultUniAsserter uniAsserter, CompletableFuture<Object> future) {
             this.testInstance = testInstance;
             this.future = future;
@@ -172,4 +196,68 @@ public void accept(Throwable t) {
         }
     }
 
+    public static class RunTestMethodOnVertxBlockingContextHandler implements Handler<Promise<Object>> {
+        private static final Runnable DO_NOTHING = new Runnable() {
+            @Override
+            public void run() {
+            }
+        };
+
+        private final Object testInstance;
+        private final Method targetMethod;
+        private final List<Object> methodArgs;
+        private final DefaultUniAsserter uniAsserter;
+
+        public RunTestMethodOnVertxBlockingContextHandler(Object testInstance, Method targetMethod, List<Object> methodArgs,
+                DefaultUniAsserter uniAsserter) {
+            this.testInstance = testInstance;
+            this.targetMethod = targetMethod;
+            this.methodArgs = methodArgs;
+            this.uniAsserter = uniAsserter;
+        }
+
+        @Override
+        public void handle(Promise<Object> promise) {
+            ManagedContext requestContext = Arc.container().requestContext();
+            if (requestContext.isActive()) {
+                doRun(promise, DO_NOTHING);
+            } else {
+                requestContext.activate();
+                doRun(promise, new Runnable() {
+                    @Override
+                    public void run() {
+                        requestContext.terminate();
+                    }
+                });
+            }
+        }
+
+        private void doRun(Promise<Object> promise, Runnable onTerminate) {
+            try {
+                Object testMethodResult = targetMethod.invoke(testInstance, methodArgs.toArray(new Object[0]));
+                if (uniAsserter != null) {
+                    uniAsserter.execution.subscribe().with(new Consumer<Object>() {
+                        @Override
+                        public void accept(Object o) {
+                            onTerminate.run();
+                            promise.complete();
+                        }
+                    }, new Consumer<>() {
+                        @Override
+                        public void accept(Throwable t) {
+                            onTerminate.run();
+                            promise.fail(t);
+                        }
+                    });
+                } else {
+                    onTerminate.run();
+                    promise.complete(testMethodResult);
+                }
+            } catch (Throwable t) {
+                onTerminate.run();
+                promise.fail(t.getCause());
+            }
+        }
+    }
+
 }