diff --git a/core/runtime/src/main/java/io/quarkus/runtime/ResourceHelper.java b/core/runtime/src/main/java/io/quarkus/runtime/ResourceHelper.java
index c2250be6203f8..3d37825a5450a 100644
--- a/core/runtime/src/main/java/io/quarkus/runtime/ResourceHelper.java
+++ b/core/runtime/src/main/java/io/quarkus/runtime/ResourceHelper.java
@@ -3,6 +3,8 @@
 import java.io.InputStream;
 import java.lang.reflect.Method;
 
+import org.graalvm.home.Version;
+
 import io.quarkus.runtime.util.ClassPathUtils;
 
 /**
@@ -11,18 +13,33 @@
 public class ResourceHelper {
 
     public static void registerResources(String resource) {
-        try {
-            Class<?> resourcesClass = Class.forName("com.oracle.svm.core.jdk.Resources");
-            Method register = resourcesClass.getDeclaredMethod("registerResource", String.class, InputStream.class);
-            ClassPathUtils.consumeAsStreams(ResourceHelper.class.getClassLoader(), resource, in -> {
-                try {
-                    register.invoke(null, resource, in);
-                } catch (Exception e) {
-                    throw new RuntimeException("Failed to register resource " + resource, e);
-                }
-            });
-        } catch (Exception e) {
-            throw new RuntimeException("Failed to load resource " + resource, e);
+        Version currentGraalVmVersion = Version.getCurrent();
+        if (currentGraalVmVersion.compareTo(22, 3) >= 0) {
+            // Use the public API RuntimeResourceAccess with GraalVM >= 22.3
+            // TODO: Remove reflective access once support for GraalVM < 22.3 gets dropped and directly invoke
+            // RuntimeResourceAccess.addResource(ClassLoader.getSystemClassLoader().getUnnamedModule(), resource);
+            try {
+                Class<?> runtimeResourceSupportClass = Class.forName("org.graalvm.nativeimage.hosted.RuntimeResourceAccess");
+                Method addResource = runtimeResourceSupportClass.getDeclaredMethod("addResource", Module.class, String.class);
+                addResource.invoke(null, ClassLoader.getSystemClassLoader().getUnnamedModule(), resource);
+            } catch (Exception e) {
+                throw new RuntimeException("Failed to load resource " + resource, e);
+            }
+        } else {
+            // Use internal API with GraalVM < 22.3
+            try {
+                Class<?> resourcesClass = Class.forName("com.oracle.svm.core.jdk.Resources");
+                Method register = resourcesClass.getDeclaredMethod("registerResource", String.class, InputStream.class);
+                ClassPathUtils.consumeAsStreams(ResourceHelper.class.getClassLoader(), resource, in -> {
+                    try {
+                        register.invoke(null, resource, in);
+                    } catch (Exception e) {
+                        throw new RuntimeException("Failed to register resource " + resource, e);
+                    }
+                });
+            } catch (Exception e) {
+                throw new RuntimeException("Failed to load resource " + resource, e);
+            }
         }
     }