diff --git a/extensions/picocli/deployment/src/main/java/io/quarkus/picocli/deployment/PicocliNativeImageProcessor.java b/extensions/picocli/deployment/src/main/java/io/quarkus/picocli/deployment/PicocliNativeImageProcessor.java
index d813694d62b5c..d301acd20b2b1 100644
--- a/extensions/picocli/deployment/src/main/java/io/quarkus/picocli/deployment/PicocliNativeImageProcessor.java
+++ b/extensions/picocli/deployment/src/main/java/io/quarkus/picocli/deployment/PicocliNativeImageProcessor.java
@@ -4,6 +4,7 @@
 import java.util.Arrays;
 import java.util.Collection;
 import java.util.HashSet;
+import java.util.List;
 import java.util.Objects;
 import java.util.Set;
 import java.util.stream.Collectors;
@@ -11,10 +12,12 @@
 import org.jboss.jandex.AnnotationInstance;
 import org.jboss.jandex.AnnotationTarget;
 import org.jboss.jandex.AnnotationValue;
+import org.jboss.jandex.AnnotationValue.Kind;
 import org.jboss.jandex.ClassInfo;
 import org.jboss.jandex.DotName;
 import org.jboss.jandex.FieldInfo;
 import org.jboss.jandex.IndexView;
+import org.jboss.jandex.Type;
 import org.jboss.logging.Logger;
 
 import io.quarkus.deployment.annotations.BuildProducer;
@@ -32,9 +35,6 @@ public class PicocliNativeImageProcessor {
 
     private static final Logger LOGGER = Logger.getLogger(PicocliNativeImageProcessor.class);
 
-    private static final DotName PARAMETERS = DotName.createSimple(CommandLine.Parameters.class.getName());
-    private static final String PARAMETERS_COMPLETION_CANDIDATES = "completionCandidates";
-
     @BuildStep(onlyIf = NativeBuild.class)
     void reflectionConfiguration(CombinedIndexBuildItem combinedIndexBuildItem,
             BuildProducer<ReflectiveFieldBuildItem> reflectiveFields,
@@ -48,13 +48,15 @@ void reflectionConfiguration(CombinedIndexBuildItem combinedIndexBuildItem,
                 DotName.createSimple(CommandLine.Command.class.getName()),
                 DotName.createSimple(CommandLine.Mixin.class.getName()),
                 DotName.createSimple(CommandLine.Option.class.getName()),
-                PARAMETERS,
+                DotName.createSimple(CommandLine.Parameters.class.getName()),
                 DotName.createSimple(CommandLine.ParentCommand.class.getName()),
                 DotName.createSimple(CommandLine.Spec.class.getName()),
                 DotName.createSimple(CommandLine.Unmatched.class.getName()));
 
         Set<ClassInfo> foundClasses = new HashSet<>();
         Set<FieldInfo> foundFields = new HashSet<>();
+        Set<Type> typeAnnotationValues = new HashSet<>();
+
         for (DotName analyzedAnnotation : annotationsToAnalyze) {
             for (AnnotationInstance ann : index.getAnnotations(analyzedAnnotation)) {
                 AnnotationTarget target = ann.target();
@@ -78,13 +80,21 @@ void reflectionConfiguration(CombinedIndexBuildItem combinedIndexBuildItem,
                         LOGGER.warnf("Unsupported type %s annotated with %s", target.kind().name(), analyzedAnnotation);
                         break;
                 }
+
+                // register classes references in Picocli annotations for reflection
+                List<AnnotationValue> values = ann.valuesWithDefaults(index);
+                for (AnnotationValue value : values) {
+                    if (value.kind() == Kind.CLASS) {
+                        typeAnnotationValues.add(value.asClass());
+                    } else if (value.kind() == Kind.ARRAY && value.componentKind() == Kind.CLASS) {
+                        for (Type componentClass : value.asClassArray()) {
+                            typeAnnotationValues.add(componentClass);
+                        }
+                    }
+                }
             }
         }
 
-        Arrays.asList(DotName.createSimple(CommandLine.IVersionProvider.class.getName()),
-                DotName.createSimple(CommandLine.class.getName()))
-                .forEach(interfaceName -> foundClasses.addAll(index.getAllKnownImplementors(interfaceName)));
-
         foundClasses.forEach(classInfo -> {
             if (Modifier.isInterface(classInfo.flags())) {
                 nativeImageProxies
@@ -97,22 +107,10 @@ void reflectionConfiguration(CombinedIndexBuildItem combinedIndexBuildItem,
             }
         });
         foundFields.forEach(fieldInfo -> reflectiveFields.produce(new ReflectiveFieldBuildItem(fieldInfo)));
-
-        // register @Parameters(completionCandidates = ...) for reflection
-        Collection<AnnotationInstance> parametersAnnotationInstances = index
-                .getAnnotations(PARAMETERS);
-        for (AnnotationInstance parametersAnnotationInstance : parametersAnnotationInstances) {
-            AnnotationValue completionCandidates = parametersAnnotationInstance.value(PARAMETERS_COMPLETION_CANDIDATES);
-
-            if (completionCandidates == null) {
-                continue;
-            }
-
-            reflectiveHierarchies.produce(new ReflectiveHierarchyBuildItem.Builder()
-                    .type(completionCandidates.asClass())
-                    .source(PicocliNativeImageProcessor.class.getSimpleName() + " > " + parametersAnnotationInstance.target())
-                    .build());
-        }
+        typeAnnotationValues.forEach(type -> reflectiveHierarchies.produce(new ReflectiveHierarchyBuildItem.Builder()
+                .type(type)
+                .source(PicocliNativeImageProcessor.class.getSimpleName())
+                .build()));
     }
 
     @BuildStep(onlyIf = NativeBuild.class)
diff --git a/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/CustomDefaultValueProvider.java b/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/CustomDefaultValueProvider.java
new file mode 100644
index 0000000000000..eff3cceedcff2
--- /dev/null
+++ b/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/CustomDefaultValueProvider.java
@@ -0,0 +1,12 @@
+package io.quarkus.it.picocli;
+
+import picocli.CommandLine.IDefaultValueProvider;
+import picocli.CommandLine.Model.ArgSpec;
+
+public class CustomDefaultValueProvider implements IDefaultValueProvider {
+
+    @Override
+    public String defaultValue(ArgSpec argSpec) throws Exception {
+        return "false";
+    }
+}
diff --git a/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/DefaultValueProviderCommand.java b/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/DefaultValueProviderCommand.java
new file mode 100644
index 0000000000000..5b22fce355b87
--- /dev/null
+++ b/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/DefaultValueProviderCommand.java
@@ -0,0 +1,12 @@
+package io.quarkus.it.picocli;
+
+import picocli.CommandLine;
+
+@CommandLine.Command(name = "defaultvalueprovider", mixinStandardHelpOptions = true, defaultValueProvider = CustomDefaultValueProvider.class)
+public class DefaultValueProviderCommand implements Runnable {
+
+    @Override
+    public void run() {
+    }
+
+}
diff --git a/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/TestResource.java b/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/TestResource.java
index 2dc9d3332535a..6c6f9d7d0f861 100644
--- a/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/TestResource.java
+++ b/integration-tests/picocli-native/src/main/java/io/quarkus/it/picocli/TestResource.java
@@ -41,6 +41,7 @@ public String getTestResults() throws UnknownHostException {
         testUnmatched();
         testI18s();
         testCompletionReflection();
+        testDefaultValueProvider();
         return "OK";
     }
 
@@ -115,4 +116,9 @@ private void testCompletionReflection() {
         CommandLine completionReflectionCommand = new CommandLine(CompletionReflectionCommand.class, factory);
         completionReflectionCommand.execute("one");
     }
+
+    private void testDefaultValueProvider() {
+        CommandLine cmd = new CommandLine(DefaultValueProviderCommand.class, factory);
+        Assertions.assertThat(cmd.execute()).isZero();
+    }
 }