diff --git a/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceIT.java b/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceIT.java
index f5c9009658985..6b544f107015a 100644
--- a/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceIT.java
+++ b/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceIT.java
@@ -1,8 +1,25 @@
 package io.quarkus.it.vertx;
 
+import static io.restassured.RestAssured.given;
+import static org.hamcrest.Matchers.containsString;
+
+import org.junit.jupiter.api.Test;
+
 import io.quarkus.test.junit.NativeImageTest;
+import io.restassured.builder.RequestSpecBuilder;
+import io.restassured.specification.RequestSpecification;
 
 @NativeImageTest
 public class VertxProducerResourceIT extends VertxProducerResourceTest {
 
-}
\ No newline at end of file
+    @Test
+    public void testRouteRegistrationMTLS() {
+        RequestSpecification spec = new RequestSpecBuilder()
+                .setBaseUri(String.format("%s://%s", url.getProtocol(), url.getHost()))
+                .setPort(8443)
+                .setKeyStore("client-keystore.jks", "password")
+                .setTrustStore("client-truststore.jks", "password")
+                .build();
+        given().spec(spec).get("/my-path").then().body(containsString("OK"));
+    }
+}
diff --git a/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceTest.java b/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceTest.java
index 5d9ff7450a2d4..33c9e89523725 100644
--- a/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceTest.java
+++ b/integration-tests/vertx-http/src/test/java/io/quarkus/it/vertx/VertxProducerResourceTest.java
@@ -9,6 +9,7 @@
 import org.junit.jupiter.api.Test;
 
 import io.quarkus.test.common.http.TestHTTPResource;
+import io.quarkus.test.junit.DisabledOnSubstrate;
 import io.quarkus.test.junit.QuarkusTest;
 import io.restassured.builder.RequestSpecBuilder;
 import io.restassured.specification.RequestSpecification;
@@ -29,6 +30,7 @@ public void testRouteRegistration() {
         get("/my-path").then().body(containsString("OK"));
     }
 
+    @DisabledOnSubstrate
     @Test
     public void testRouteRegistrationMTLS() {
         RequestSpecification spec = new RequestSpecBuilder()