diff --git a/extensions/hibernate-orm/deployment/src/main/java/io/quarkus/hibernate/orm/deployment/HibernateOrmProcessor.java b/extensions/hibernate-orm/deployment/src/main/java/io/quarkus/hibernate/orm/deployment/HibernateOrmProcessor.java
index cced0279109e9..ed0354c6797a0 100644
--- a/extensions/hibernate-orm/deployment/src/main/java/io/quarkus/hibernate/orm/deployment/HibernateOrmProcessor.java
+++ b/extensions/hibernate-orm/deployment/src/main/java/io/quarkus/hibernate/orm/deployment/HibernateOrmProcessor.java
@@ -17,6 +17,7 @@
 import java.util.HashSet;
 import java.util.LinkedHashSet;
 import java.util.List;
+import java.util.Locale;
 import java.util.Map;
 import java.util.Map.Entry;
 import java.util.Optional;
@@ -555,7 +556,7 @@ private void handleHibernateORMWithNoPersistenceXml(
                 .filter(i -> i.isDefault())
                 .findFirst();
 
-        Set<String> storageEngines = new HashSet<>();
+        Set<String> storageEngineCollector = new HashSet<>();
 
         if ((defaultJdbcDataSource.isPresent() && hibernateOrmConfig.persistenceUnits.isEmpty()) ||
                 hibernateOrmConfig.defaultPersistenceUnit.isAnyPropertySet()) {
@@ -565,11 +566,8 @@ private void handleHibernateORMWithNoPersistenceXml(
                     modelClassesPerPersistencesUnits.getOrDefault(PersistenceUnitUtil.DEFAULT_PERSISTENCE_UNIT_NAME,
                             Collections.emptySet()),
                     jdbcDataSources, applicationArchivesBuildItem, launchMode, capabilities,
-                    systemProperties, nativeImageResources, hotDeploymentWatchedFiles, persistenceUnitDescriptors);
-
-            if (hibernateOrmConfig.defaultPersistenceUnit.dialect.storageEngine.isPresent()) {
-                storageEngines.add(hibernateOrmConfig.defaultPersistenceUnit.dialect.storageEngine.get());
-            }
+                    systemProperties, nativeImageResources, hotDeploymentWatchedFiles, persistenceUnitDescriptors,
+                    storageEngineCollector);
         }
 
         for (Entry<String, HibernateOrmConfigPersistenceUnit> persistenceUnitEntry : hibernateOrmConfig.persistenceUnits
@@ -578,14 +576,11 @@ private void handleHibernateORMWithNoPersistenceXml(
                     hibernateOrmConfig, persistenceUnitEntry.getKey(), persistenceUnitEntry.getValue(),
                     modelClassesPerPersistencesUnits.getOrDefault(persistenceUnitEntry.getKey(), Collections.emptySet()),
                     jdbcDataSources, applicationArchivesBuildItem, launchMode, capabilities,
-                    systemProperties, nativeImageResources, hotDeploymentWatchedFiles, persistenceUnitDescriptors);
-
-            if (persistenceUnitEntry.getValue().dialect.storageEngine.isPresent()) {
-                storageEngines.add(persistenceUnitEntry.getValue().dialect.storageEngine.get());
-            }
+                    systemProperties, nativeImageResources, hotDeploymentWatchedFiles, persistenceUnitDescriptors,
+                    storageEngineCollector);
         }
 
-        if (storageEngines.size() > 1) {
+        if (storageEngineCollector.size() > 1) {
             throw new ConfigurationException(
                     "The dialect storage engine is a global configuration property: it must be consistent across all persistence units.");
         }
@@ -603,7 +598,8 @@ private static void producePersistenceUnitDescriptorFromConfig(
             BuildProducer<SystemPropertyBuildItem> systemProperties,
             BuildProducer<NativeImageResourceBuildItem> nativeImageResources,
             BuildProducer<HotDeploymentWatchedFileBuildItem> hotDeploymentWatchedFiles,
-            BuildProducer<PersistenceUnitDescriptorBuildItem> persistenceUnitDescriptors) {
+            BuildProducer<PersistenceUnitDescriptorBuildItem> persistenceUnitDescriptors,
+            Set<String> storageEngineCollector) {
         // Find the associated datasource
         JdbcDataSourceBuildItem jdbcDataSource;
         String dataSource;
@@ -786,6 +782,11 @@ private static void producePersistenceUnitDescriptorFromConfig(
             descriptor.getProperties().setProperty(AvailableSettings.JPA_VALIDATION_MODE, ValidationMode.CALLBACK.name());
         }
 
+        // Collect the storage engines if MySQL or MariaDB
+        if (isMySQLOrMariaDB(dialect.get()) && persistenceUnitConfig.dialect.storageEngine.isPresent()) {
+            storageEngineCollector.add(persistenceUnitConfig.dialect.storageEngine.get());
+        }
+
         persistenceUnitDescriptors.produce(
                 new PersistenceUnitDescriptorBuildItem(descriptor, dataSource,
                         getMultiTenancyStrategy(hibernateOrmConfig),
@@ -999,4 +1000,9 @@ private static Class[] toArray(final Set<Class<?>> interfaces) {
         }
         return interfaces.toArray(new Class[interfaces.size()]);
     }
+
+    private static boolean isMySQLOrMariaDB(String dialect) {
+        String lowercaseDialect = dialect.toLowerCase(Locale.ROOT);
+        return lowercaseDialect.contains("mysql") || lowercaseDialect.contains("mariadb");
+    }
 }
diff --git a/extensions/hibernate-orm/deployment/src/test/java/io/quarkus/hibernate/orm/multiplepersistenceunits/MultiplePersistenceUnitsInconsistentStorageEnginesTest.java b/extensions/hibernate-orm/deployment/src/test/java/io/quarkus/hibernate/orm/multiplepersistenceunits/MultiplePersistenceUnitsInconsistentStorageEnginesTest.java
index 7f9608cc8df04..e9b985539d6c4 100644
--- a/extensions/hibernate-orm/deployment/src/test/java/io/quarkus/hibernate/orm/multiplepersistenceunits/MultiplePersistenceUnitsInconsistentStorageEnginesTest.java
+++ b/extensions/hibernate-orm/deployment/src/test/java/io/quarkus/hibernate/orm/multiplepersistenceunits/MultiplePersistenceUnitsInconsistentStorageEnginesTest.java
@@ -1,5 +1,6 @@
 package io.quarkus.hibernate.orm.multiplepersistenceunits;
 
+import org.hibernate.dialect.H2Dialect;
 import org.jboss.shrinkwrap.api.ShrinkWrap;
 import org.jboss.shrinkwrap.api.spec.JavaArchive;
 import org.junit.jupiter.api.Assertions;
@@ -30,4 +31,10 @@ public void testInvalidConfiguration() {
         // deployment exception should happen first
         Assertions.fail();
     }
+
+    /**
+     * This is just to have the dialect matching MySQL and trigger the MySQL + storage engines check.
+     */
+    public static class H2DialectWithMySQLInTheName extends H2Dialect {
+    }
 }
diff --git a/extensions/hibernate-orm/deployment/src/test/resources/application-multiple-persistence-units-inconsistent-storage-engines.properties b/extensions/hibernate-orm/deployment/src/test/resources/application-multiple-persistence-units-inconsistent-storage-engines.properties
index 439a990e889c3..c96d09e31c934 100644
--- a/extensions/hibernate-orm/deployment/src/test/resources/application-multiple-persistence-units-inconsistent-storage-engines.properties
+++ b/extensions/hibernate-orm/deployment/src/test/resources/application-multiple-persistence-units-inconsistent-storage-engines.properties
@@ -7,18 +7,18 @@ quarkus.datasource.users.jdbc.url=jdbc:h2:mem:users;DB_CLOSE_DELAY=-1
 quarkus.datasource.inventory.db-kind=h2
 quarkus.datasource.inventory.jdbc.url=jdbc:h2:mem:inventory;DB_CLOSE_DELAY=-1
 
-quarkus.hibernate-orm.dialect=org.hibernate.dialect.H2Dialect
+quarkus.hibernate-orm.dialect=io.quarkus.hibernate.orm.multiplepersistenceunits.MultiplePersistenceUnitsInconsistentStorageEnginesTest$H2DialectWithMySQLInTheName
 quarkus.hibernate-orm.dialect.storage-engine=engine1
 quarkus.hibernate-orm.database.generation=drop-and-create
 quarkus.hibernate-orm.packages=io.quarkus.hibernate.orm.multiplepersistenceunits.model
 
-quarkus.hibernate-orm."users".dialect=org.hibernate.dialect.H2Dialect
+quarkus.hibernate-orm."users".dialect=io.quarkus.hibernate.orm.multiplepersistenceunits.MultiplePersistenceUnitsInconsistentStorageEnginesTest$H2DialectWithMySQLInTheName
 quarkus.hibernate-orm."users".dialect.storage-engine=engine2
 quarkus.hibernate-orm."users".database.generation=drop-and-create
 quarkus.hibernate-orm."users".datasource=users
 quarkus.hibernate-orm."users".packages=io.quarkus.hibernate.orm.multiplepersistenceunits.model.user
 
-quarkus.hibernate-orm."inventory".dialect=org.hibernate.dialect.H2Dialect
+quarkus.hibernate-orm."inventory".dialect=io.quarkus.hibernate.orm.multiplepersistenceunits.MultiplePersistenceUnitsInconsistentStorageEnginesTest$H2DialectWithMySQLInTheName
 quarkus.hibernate-orm."inventory".database.generation=drop-and-create
 quarkus.hibernate-orm."inventory".datasource=inventory
 quarkus.hibernate-orm."inventory".packages=io.quarkus.hibernate.orm.multiplepersistenceunits.model.inventory