diff --git a/Lib/ensurepip/__init__.py b/Lib/ensurepip/__init__.py
index 2a140a2624d461..e510cc7fb2bafd 100644
--- a/Lib/ensurepip/__init__.py
+++ b/Lib/ensurepip/__init__.py
@@ -12,7 +12,7 @@
 
 __all__ = ["version", "bootstrap"]
 _SETUPTOOLS_VERSION = "58.1.0"
-_PIP_VERSION = "21.2.4"
+_PIP_VERSION = "22.0.4"
 _PROJECTS = [
     ("setuptools", _SETUPTOOLS_VERSION, "py3"),
     ("pip", _PIP_VERSION, "py3"),
diff --git a/Lib/ensurepip/_bundled/pip-21.2.4-py3-none-any.whl b/Lib/ensurepip/_bundled/pip-21.2.4-py3-none-any.whl
deleted file mode 100644
index 46d3012c59b174..00000000000000
Binary files a/Lib/ensurepip/_bundled/pip-21.2.4-py3-none-any.whl and /dev/null differ
diff --git a/Lib/ensurepip/_bundled/pip-22.0.4-py3-none-any.whl b/Lib/ensurepip/_bundled/pip-22.0.4-py3-none-any.whl
new file mode 100644
index 00000000000000..7ba048e245227d
Binary files /dev/null and b/Lib/ensurepip/_bundled/pip-22.0.4-py3-none-any.whl differ
diff --git a/Misc/NEWS.d/next/Library/2022-03-11-13-34-16.bpo-46985.BgoMr2.rst b/Misc/NEWS.d/next/Library/2022-03-11-13-34-16.bpo-46985.BgoMr2.rst
new file mode 100644
index 00000000000000..2e08ee837f583b
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2022-03-11-13-34-16.bpo-46985.BgoMr2.rst
@@ -0,0 +1 @@
+Upgrade pip wheel bundled with ensurepip (pip 22.0.4)