diff --git a/news/6106.removal b/news/6106.removal
new file mode 100644
index 00000000000..56bd9a9c7ff
--- /dev/null
+++ b/news/6106.removal
@@ -0,0 +1 @@
+Deprecate support for Python 3.4
diff --git a/src/pip/_internal/cli/base_command.py b/src/pip/_internal/cli/base_command.py
index a8371aa8754..e1f45826ce4 100644
--- a/src/pip/_internal/cli/base_command.py
+++ b/src/pip/_internal/cli/base_command.py
@@ -26,6 +26,7 @@
     install_req_from_editable, install_req_from_line,
 )
 from pip._internal.req.req_file import parse_requirements
+from pip._internal.utils.deprecation import deprecated
 from pip._internal.utils.logging import setup_logging
 from pip._internal.utils.misc import (
     get_prog, normalize_path, redact_password_from_url,
@@ -134,6 +135,15 @@ def main(self, args):
             user_log_file=options.log,
         )
 
+        if sys.version_info[:2] == (3, 4):
+            deprecated(
+                "Python 3.4 support has been deprecated. pip 19.1 will be the "
+                "last one supporting it. Please upgrade your Python as Python "
+                "3.4 won't be maintained after March 2019 (cf PEP 429).",
+                replacement=None,
+                gone_in='19.2',
+            )
+
         # TODO: Try to get these passing down from the command?
         #       without resorting to os.environ to hold these.
         #       This also affects isolated builds and it should.
diff --git a/tests/conftest.py b/tests/conftest.py
index a7bf81c5b6d..1b51fc8d322 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -349,4 +349,4 @@ def in_memory_pip():
 @pytest.fixture
 def deprecated_python():
     """Used to indicate wheither pip deprecated this python version"""
-    return False
+    return sys.version_info[:2] == (3, 4)