diff --git a/news/9444.bugfix.rst b/news/9444.bugfix.rst
new file mode 100644
index 00000000000..4cba93e42ff
--- /dev/null
+++ b/news/9444.bugfix.rst
@@ -0,0 +1 @@
+Permit ``pip uninstall -r`` to accept requirements files containing ``--install-option`` or ``--global-option``.
diff --git a/src/pip/_internal/cli/cmdoptions.py b/src/pip/_internal/cli/cmdoptions.py
index 24dc9d14107..46cb229f83a 100644
--- a/src/pip/_internal/cli/cmdoptions.py
+++ b/src/pip/_internal/cli/cmdoptions.py
@@ -75,8 +75,9 @@ def getname(n):
         return getattr(check_options, n, None)
 
     names = ["build_options", "global_options", "install_options"]
-    if any(map(getname, names)):
-        control = options.format_control
+
+    control = getattr(options, "format_control", None)
+    if control and any(map(getname, names)):
         control.disallow_binaries()
         warnings.warn(
             "Disabling all use of wheels due to the use of --build-option "