diff --git a/CHANGELOG.md b/CHANGELOG.md
index 37902279..59428d3d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -8,6 +8,12 @@ All versions prior to 0.0.9 are untracked.
 
 ## [Unreleased]
 
+### Changed
+
+* Improved error message for when unpinned URL requirements are found during an
+  audit with the `--no-deps` flag
+  ([#355](https://github.com/trailofbits/pip-audit/pull/355))
+
 ### Fixed
 
 * Fixed an issue where packages on PyPI with no published versions trigger a
diff --git a/pip_audit/_dependency_source/requirement.py b/pip_audit/_dependency_source/requirement.py
index d4a1b25c..92a97f1e 100644
--- a/pip_audit/_dependency_source/requirement.py
+++ b/pip_audit/_dependency_source/requirement.py
@@ -251,7 +251,15 @@ def _collect_preresolved_deps(
                 )
 
             if not req.specifier:
-                raise RequirementSourceError(f"requirement {req.name} is not pinned: {str(req)}")
+                if req.link is None:
+                    raise RequirementSourceError(
+                        f"requirement {req.name} is not pinned: {str(req)}"
+                    )
+                else:
+                    raise RequirementSourceError(
+                        f"requirement {req.name} is not pinned, URL requirements must be pinned "
+                        f"with #egg=your_package_name==your_package_version: {str(req)}"
+                    )
 
             pinned_specifier = PINNED_SPECIFIER_RE.match(str(req.specifier))
             if pinned_specifier is None:
diff --git a/test/dependency_source/test_requirement.py b/test/dependency_source/test_requirement.py
index 786cb272..c916791c 100644
--- a/test/dependency_source/test_requirement.py
+++ b/test/dependency_source/test_requirement.py
@@ -443,6 +443,23 @@ def test_requirement_source_no_deps_unpinned(monkeypatch):
         list(source.collect())
 
 
+def test_requirement_source_no_deps_unpinned_url(monkeypatch):
+    source = requirement.RequirementSource(
+        [Path("requirements.txt")], ResolveLibResolver(), no_deps=True
+    )
+
+    monkeypatch.setattr(
+        pip_requirements_parser,
+        "get_file_content",
+        lambda _: "https://github.com/pallets/flask/archive/refs/tags/2.0.1.tar.gz#egg=flask\n"
+        "requests>=1.0",
+    )
+
+    # When dependency resolution is disabled, all requirements must be pinned.
+    with pytest.raises(DependencySourceError):
+        list(source.collect())
+
+
 def test_requirement_source_dep_caching(monkeypatch):
     source = requirement.RequirementSource(
         [Path("requirements.txt")], ResolveLibResolver(), no_deps=True