diff --git a/examples/common/pigweed/BUILD.gn b/examples/common/pigweed/BUILD.gn
index 2d5b69c1b8d4ce..653bc0515d55d8 100644
--- a/examples/common/pigweed/BUILD.gn
+++ b/examples/common/pigweed/BUILD.gn
@@ -82,11 +82,14 @@ pw_source_set("system_rpc_server") {
   sources = [ "system_rpc_server.cc" ]
 
   deps = [
+    "$dir_pw_rpc/system_server:facade",
+    dir_pw_log,
+  ]
+
+  public_deps = [
     "$dir_pw_hdlc:pw_rpc",
     "$dir_pw_hdlc:rpc_channel_output",
-    "$dir_pw_rpc/system_server:facade",
     "$dir_pw_stream:sys_io_stream",
-    dir_pw_log,
   ]
 
   public_configs = [ ":default_config" ]
diff --git a/integrations/cloudbuild/smoke-test.yaml b/integrations/cloudbuild/smoke-test.yaml
index 62aad0dfaa2964..1e45d762440c8b 100644
--- a/integrations/cloudbuild/smoke-test.yaml
+++ b/integrations/cloudbuild/smoke-test.yaml
@@ -35,7 +35,7 @@ steps:
       args:
           - >-
               ./scripts/build/build_examples.py --enable-flashbundle
-              --target-glob '*-nrf52840-{lock,light}' build --create-archives
+              --target-glob '*-nrf52840-{lock,light}*' build --create-archives
               /workspace/artifacts/
       waitFor:
           - Bootstrap
@@ -52,8 +52,8 @@ steps:
       args:
           - >-
               ./scripts/build/build_examples.py --enable-flashbundle
-              --target-glob '*-brd4161a-{lock,light}' build --create-archives
-              /workspace/artifacts/
+              --target-glob '*-brd4161a-{lock,light,unit-test}*' build
+              --create-archives /workspace/artifacts/
       waitFor:
           - Bootstrap
           - NRFConnect
diff --git a/scripts/build/build/targets.py b/scripts/build/build/targets.py
index da3a2a830821f7..bfe09d3128103c 100644
--- a/scripts/build/build/targets.py
+++ b/scripts/build/build/targets.py
@@ -144,6 +144,7 @@ def Efr32Targets():
 
     yield efr_target.Extend('window-covering', app=Efr32App.WINDOW_COVERING)
     yield efr_target.Extend('lock', app=Efr32App.LOCK)
+    yield efr_target.Extend('unit-test', app=Efr32App.UNIT_TEST)
 
     rpc_aware_targets = [
         efr_target.Extend('light', app=Efr32App.LIGHT),
diff --git a/scripts/build/builders/efr32.py b/scripts/build/builders/efr32.py
index 41c4acb54369c5..4f90419291bb6c 100644
--- a/scripts/build/builders/efr32.py
+++ b/scripts/build/builders/efr32.py
@@ -22,6 +22,7 @@ class Efr32App(Enum):
     LIGHT = auto()
     LOCK = auto()
     WINDOW_COVERING = auto()
+    UNIT_TEST = auto()
 
     def ExampleName(self):
         if self == Efr32App.LIGHT:
@@ -40,6 +41,8 @@ def AppNamePrefix(self):
             return 'chip-efr32-lock-example'
         elif self == Efr32App.WINDOW_COVERING:
             return 'chip-efr32-window-example'
+        elif self == Efr32App.UNIT_TEST:
+            return 'chip-efr32-device_tests'
         else:
             raise Exception('Unknown app type: %r' % self)
 
@@ -50,9 +53,17 @@ def FlashBundleName(self):
             return 'lock_app.flashbundle.txt'
         elif self == Efr32App.WINDOW_COVERING:
             return 'window_app.flashbundle.txt'
+        elif self == Efr32App.UNIT_TEST:
+            return 'efr32_device_tests.flashbundle.txt'
         else:
             raise Exception('Unknown app type: %r' % self)
 
+    def BuildRoot(self, root):
+        if self == Efr32App.UNIT_TEST:
+            return os.path.join(root, 'src', 'test_driver', 'efr32')
+        else:
+            return os.path.join(root, 'examples', self.ExampleName(), 'efr32')
+
 
 class Efr32Board(Enum):
     BRD4161A = 1
@@ -71,7 +82,7 @@ def __init__(self,
                  board: Efr32Board = Efr32Board.BRD4161A,
                  enable_rpcs: bool = False):
         super(Efr32Builder, self).__init__(
-            root=os.path.join(root, 'examples', app.ExampleName(), 'efr32'),
+            root=app.BuildRoot(root),
             runner=runner)
         self.app = app
         self.board = board
@@ -93,6 +104,11 @@ def build_outputs(self):
                              '%s.out.map' % self.app.AppNamePrefix()),
         }
 
+        if self.app == Efr32App.UNIT_TEST:
+            # Include test runner python wheels
+            items["chip_nl_test_runner_wheels"] = os.path.join(
+                self.output_dir, 'chip_nl_test_runner_wheels')
+
         # Figure out flash bundle files and build accordingly
         with open(os.path.join(self.output_dir, self.app.FlashBundleName())) as f:
             for line in f.readlines():
diff --git a/scripts/build/testdata/all_targets_except_host.txt b/scripts/build/testdata/all_targets_except_host.txt
index 7324824301a35d..62abd8211112f8 100644
--- a/scripts/build/testdata/all_targets_except_host.txt
+++ b/scripts/build/testdata/all_targets_except_host.txt
@@ -12,6 +12,7 @@ android-x86-chip-tool
 efr32-brd4161a-light
 efr32-brd4161a-light-rpc
 efr32-brd4161a-lock
+efr32-brd4161a-unit-test
 efr32-brd4161a-window-covering
 esp32-c3devkit-all-clusters
 esp32-devkitc-all-clusters
diff --git a/scripts/build/testdata/build_all_except_host.txt b/scripts/build/testdata/build_all_except_host.txt
index f928f42467e56f..bea6e68bc04ed8 100644
--- a/scripts/build/testdata/build_all_except_host.txt
+++ b/scripts/build/testdata/build_all_except_host.txt
@@ -133,6 +133,9 @@ gn gen --check --fail-on-unused-args --root={root}/examples/lighting-app/efr32 '
 # Generating efr32-brd4161a-lock
 gn gen --check --fail-on-unused-args --root={root}/examples/lock-app/efr32 '--args=efr32_board="BRD4161A"' {out}/efr32-brd4161a-lock
 
+# Generating efr32-brd4161a-unit-test
+gn gen --check --fail-on-unused-args --root={root}/src/test_driver/efr32 '--args=efr32_board="BRD4161A"' {out}/efr32-brd4161a-unit-test
+
 # Generating efr32-brd4161a-window-covering
 gn gen --check --fail-on-unused-args --root={root}/examples/window-app/efr32 '--args=efr32_board="BRD4161A"' {out}/efr32-brd4161a-window-covering
 
@@ -606,6 +609,9 @@ ninja -C {out}/efr32-brd4161a-light-rpc
 # Building efr32-brd4161a-lock
 ninja -C {out}/efr32-brd4161a-lock
 
+# Building efr32-brd4161a-unit-test
+ninja -C {out}/efr32-brd4161a-unit-test
+
 # Building efr32-brd4161a-window-covering
 ninja -C {out}/efr32-brd4161a-window-covering
 
diff --git a/scripts/build/testdata/glob_star_targets_except_host.txt b/scripts/build/testdata/glob_star_targets_except_host.txt
index 8ef68760e5175e..a78108879d08eb 100644
--- a/scripts/build/testdata/glob_star_targets_except_host.txt
+++ b/scripts/build/testdata/glob_star_targets_except_host.txt
@@ -12,6 +12,7 @@ android-x86-chip-tool
 efr32-brd4161a-light
 efr32-brd4161a-light-rpc
 efr32-brd4161a-lock
+efr32-brd4161a-unit-test
 efr32-brd4161a-window-covering
 esp32-c3devkit-all-clusters
 esp32-devkitc-all-clusters
diff --git a/src/BUILD.gn b/src/BUILD.gn
index 3c226c5fdb61de..79e18e0afc490a 100644
--- a/src/BUILD.gn
+++ b/src/BUILD.gn
@@ -45,7 +45,6 @@ if (chip_build_tests) {
   chip_test_group("tests") {
     deps = [
       "${chip_root}/src/access/tests",
-      "${chip_root}/src/app/tests",
       "${chip_root}/src/crypto/tests",
       "${chip_root}/src/inet/tests",
       "${chip_root}/src/lib/asn1/tests",
@@ -74,6 +73,8 @@ if (chip_build_tests) {
 
     if (chip_device_platform != "efr32") {
       deps += [
+        # TODO(#10447): App test has HF on EFR32.
+        "${chip_root}/src/app/tests",
         "${chip_root}/src/credentials/tests",
         "${chip_root}/src/lib/support/tests",
         "${chip_root}/src/protocols/secure_channel/tests",
@@ -97,7 +98,9 @@ if (chip_build_tests) {
 
     # On nrfconnect, the controller tests run into
     # https://github.com/project-chip/connectedhomeip/issues/9630
-    if (chip_device_platform != "nrfconnect") {
+    if (chip_device_platform != "nrfconnect" &&
+        chip_device_platform != "efr32") {
+      # TODO(#10447): Controller test has HF on EFR32.
       deps += [ "${chip_root}/src/controller/tests" ]
     }
 
diff --git a/src/app/tests/BUILD.gn b/src/app/tests/BUILD.gn
index 4d88360a527865..1cb62b6cc93d83 100644
--- a/src/app/tests/BUILD.gn
+++ b/src/app/tests/BUILD.gn
@@ -45,24 +45,19 @@ chip_test_suite("tests") {
     "TestBuilderParser.cpp",
     "TestCHIPDeviceCallbacksMgr.cpp",
     "TestClusterInfo.cpp",
+    "TestCommandInteraction.cpp",
     "TestCommandPathParams.cpp",
     "TestDataModelSerialization.cpp",
     "TestEventLogging.cpp",
     "TestEventPathParams.cpp",
     "TestInteractionModelEngine.cpp",
     "TestMessageDef.cpp",
+    "TestReadInteraction.cpp",
+    "TestReportingEngine.cpp",
     "TestStatusResponseMessage.cpp",
+    "TestWriteInteraction.cpp",
   ]
 
-  if (chip_device_platform != "efr32") {
-    test_sources += [
-      "TestCommandInteraction.cpp",
-      "TestReadInteraction.cpp",
-      "TestReportingEngine.cpp",
-      "TestWriteInteraction.cpp",
-    ]
-  }
-
   cflags = [ "-Wconversion" ]
 
   public_deps = [
diff --git a/src/messaging/tests/BUILD.gn b/src/messaging/tests/BUILD.gn
index ce1852d03251de..bfc6ce28bd33b9 100644
--- a/src/messaging/tests/BUILD.gn
+++ b/src/messaging/tests/BUILD.gn
@@ -45,9 +45,13 @@ chip_test_suite("tests") {
   sources = [
     "TestExchangeMgr.cpp",
     "TestMessagingLayer.h",
-    "TestReliableMessageProtocol.cpp",
   ]
 
+  if (chip_device_platform != "efr32") {
+    # TODO(#10447): Test has HF on EFR32.
+    sources += [ "TestReliableMessageProtocol.cpp" ]
+  }
+
   cflags = [ "-Wconversion" ]
 
   public_deps = [
diff --git a/src/test_driver/efr32/BUILD.gn b/src/test_driver/efr32/BUILD.gn
index c333614c482cfd..d5bb25ff017f49 100644
--- a/src/test_driver/efr32/BUILD.gn
+++ b/src/test_driver/efr32/BUILD.gn
@@ -105,6 +105,7 @@ group("efr32") {
   deps = [
     ":efr32_device_tests",
     "${efr32_project_dir}/py:nl_test_runner.install",
+    "${efr32_project_dir}/py:nl_test_runner_wheel",
   ]
 }
 
diff --git a/src/test_driver/efr32/py/BUILD.gn b/src/test_driver/efr32/py/BUILD.gn
index c4d0dd0610ad61..539d56d062fe25 100644
--- a/src/test_driver/efr32/py/BUILD.gn
+++ b/src/test_driver/efr32/py/BUILD.gn
@@ -33,3 +33,9 @@ pw_python_package("nl_test_runner") {
     "${chip_root}/src/test_driver/efr32:nl_test_service.python",
   ]
 }
+
+pw_mirror_tree("nl_test_runner_wheel") {
+  path_data_keys = [ "pw_python_package_wheels" ]
+  deps = [ ":nl_test_runner.wheel" ]
+  directory = "$root_out_dir/chip_nl_test_runner_wheels"
+}
diff --git a/src/test_driver/efr32/py/nl_test_runner/nl_test_runner.py b/src/test_driver/efr32/py/nl_test_runner/nl_test_runner.py
index 1f4e5bd3f9eef0..492fc3fa8ecf22 100644
--- a/src/test_driver/efr32/py/nl_test_runner/nl_test_runner.py
+++ b/src/test_driver/efr32/py/nl_test_runner/nl_test_runner.py
@@ -89,15 +89,15 @@ def read(): return serial_device.read(8192)
 
 def runner(client) -> int:
     """ Run the tests"""
-    status, result = client.client.channel(
-        1).rpcs.chip.rpc.NlTest.Run(pw_rpc_timeout_s=120)
-
-    if not status.ok():
+    def on_error_callback(call_object, error):
         raise Exception("Error running test RPC: {}".format(status))
 
+    rpc = client.client.channel(1).rpcs.chip.rpc.NlTest.Run
+    invoke = rpc.invoke(rpc.request(), on_error=on_error_callback)
+
     total_failed = 0
     total_run = 0
-    for streamed_data in result:
+    for streamed_data in invoke.get_responses():
         if streamed_data.HasField("test_suite_start"):
             print("\n{}".format(
                 colors.HEADER + streamed_data.test_suite_start.suite_name) + colors.ENDC)