diff --git a/examples/lighting-app/nrfconnect/CMakeLists.txt b/examples/lighting-app/nrfconnect/CMakeLists.txt
index 027ab711955a05..381af2dad59761 100644
--- a/examples/lighting-app/nrfconnect/CMakeLists.txt
+++ b/examples/lighting-app/nrfconnect/CMakeLists.txt
@@ -114,14 +114,13 @@ endif()
 
 if (CONFIG_CHIP_PW_RPC)
 
+# Make all targets created below depend on zephyr_interface to inherit MCU-related compilation flags
+link_libraries($<BUILD_INTERFACE:zephyr_interface>)
+
 set(PIGWEED_ROOT "${CHIP_ROOT}/third_party/pigweed/repo")
 include(${PIGWEED_ROOT}/pw_build/pigweed.cmake)
 include(${PIGWEED_ROOT}/pw_protobuf_compiler/proto.cmake)
 
-# TODO: Remove this temporary fix needed to get RPC builds working.
-set(CMAKE_C_FLAGS "${CMAKE_C_FLAGS} -mcpu=cortex-m4 -mthumb" CACHE INTERNAL "")
-set(CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS} -mcpu=cortex-m4 -mthumb" CACHE INTERNAL "")
-
 pw_set_backend(pw_log pw_log_basic)
 pw_set_backend(pw_assert pw_assert_log)
 pw_set_backend(pw_sys_io pw_sys_io.nrfconnect)
@@ -223,6 +222,4 @@ target_link_options(app
     "-T${PIGWEED_ROOT}/pw_tokenizer/pw_tokenizer_linker_sections.ld"
 )
 
-target_link_libraries(pw_build INTERFACE zephyr_interface)
-
 endif(CONFIG_CHIP_PW_RPC)
diff --git a/examples/lighting-app/nrfconnect/rpc.overlay b/examples/lighting-app/nrfconnect/rpc.overlay
index aee22afb4a39c5..f9f7c10f0b0954 100644
--- a/examples/lighting-app/nrfconnect/rpc.overlay
+++ b/examples/lighting-app/nrfconnect/rpc.overlay
@@ -26,9 +26,6 @@ CONFIG_CHIP_PW_RPC=y
 CONFIG_STD_CPP14=n
 CONFIG_STD_CPP17=y
 
-# Disable HW floating point, as libprotobuf nano doesn't support building with it
-CONFIG_FPU=n
-
 # Add support for Zephyr console component to use it for Pigweed console purposes
 CONFIG_CONSOLE_SUBSYS=y
 CONFIG_CONSOLE_GETCHAR=y
@@ -48,4 +45,4 @@ CONFIG_LOG_BACKEND_UART=n
 CONFIG_LOG_BACKEND_RTT=n
 
 # Increase zephyr tty rx buffer
-CONFIG_CONSOLE_GETCHAR_BUFSIZE=128
\ No newline at end of file
+CONFIG_CONSOLE_GETCHAR_BUFSIZE=128
diff --git a/examples/pigweed-app/nrfconnect/CMakeLists.txt b/examples/pigweed-app/nrfconnect/CMakeLists.txt
index e05628bcfd8af5..e5df573ad830ab 100644
--- a/examples/pigweed-app/nrfconnect/CMakeLists.txt
+++ b/examples/pigweed-app/nrfconnect/CMakeLists.txt
@@ -43,6 +43,9 @@ include(${CHIP_ROOT}/config/nrfconnect/app/enable-gnu-std.cmake)
 # See https://gcc.gnu.org/bugzilla/show_bug.cgi?id=80635
 target_compile_options(app PRIVATE -Werror -Wno-error=maybe-uninitialized)
 
+# Make all targets created below depend on zephyr_interface to inherit MCU-related compilation flags
+link_libraries($<BUILD_INTERFACE:zephyr_interface>)
+
 include(${PIGWEED_ROOT}/pw_build/pigweed.cmake)
 include(${PIGWEED_ROOT}/pw_protobuf_compiler/proto.cmake)
 
@@ -86,6 +89,4 @@ target_link_libraries(app PUBLIC
   pw_rpc.server
 )
 
-target_link_libraries(pw_build INTERFACE zephyr_interface)
-
 include(${CHIP_ROOT}/config/nrfconnect/app/flashing.cmake)
diff --git a/examples/pigweed-app/nrfconnect/README.md b/examples/pigweed-app/nrfconnect/README.md
index a66f536180480b..d226db40338513 100644
--- a/examples/pigweed-app/nrfconnect/README.md
+++ b/examples/pigweed-app/nrfconnect/README.md
@@ -326,7 +326,7 @@ to read more about flashing on the nRF52840 Dongle.
 Run the following command to start an interactive Python shell, where the Echo
 RPC commands can be invoked:
 
-        python -m pw_hdlc.rpc_console --device /dev/ttyACM0 -b 115200 $CHIP_ROOT/third_party/pigweed/repo/pw_rpc/echo.proto -o /tmp/pw_rpc.out
+        python -m pw_hdlc.rpc_console --device /dev/ttyACM0 -b 115200 --proto-globs $CHIP_ROOT/third_party/pigweed/repo/pw_rpc/echo.proto -o /tmp/pw_rpc.out
 
 To send an Echo RPC message, type the following command, where the actual
 message is the text in quotation marks after the `msg=` phrase:
diff --git a/examples/pigweed-app/nrfconnect/prj.conf b/examples/pigweed-app/nrfconnect/prj.conf
index 0895493dcc8f72..58a0fe63277b34 100644
--- a/examples/pigweed-app/nrfconnect/prj.conf
+++ b/examples/pigweed-app/nrfconnect/prj.conf
@@ -30,9 +30,6 @@ CONFIG_CHIP_PW_RPC=y
 CONFIG_STD_CPP14=n
 CONFIG_STD_CPP17=y
 
-# Disable HW floating point, as libprotobuf nano doesn't support building with it
-CONFIG_FPU=n
-
 # Add support for Zephyr console component to use it for Pigweed console purposes
 CONFIG_CONSOLE_SUBSYS=y
 CONFIG_CONSOLE_GETCHAR=y