diff --git a/src/messaging/tests/TestReliableMessageProtocol.cpp b/src/messaging/tests/TestReliableMessageProtocol.cpp
index 5d0179743cdff9..ac717f69d99016 100644
--- a/src/messaging/tests/TestReliableMessageProtocol.cpp
+++ b/src/messaging/tests/TestReliableMessageProtocol.cpp
@@ -95,6 +95,10 @@ class MockAppDelegate : public ExchangeDelegate
                            System::PacketBufferHandle && buffer) override
     {
         IsOnMessageReceivedCalled = true;
+        if (mDropAckResponse)
+        {
+            ec->GetReliableMessageContext()->SetAckPending(false);
+        }
         ec->Close();
         if (mTestSuite != nullptr)
         {
@@ -106,8 +110,8 @@ class MockAppDelegate : public ExchangeDelegate
     void OnResponseTimeout(ExchangeContext * ec) override {}
 
     bool IsOnMessageReceivedCalled = false;
-
-    nlTestSuite * mTestSuite = nullptr;
+    bool mDropAckResponse          = false;
+    nlTestSuite * mTestSuite       = nullptr;
 };
 
 class MockSessionEstablishmentExchangeDispatch : public Messaging::ExchangeMessageDispatch
@@ -487,6 +491,91 @@ void CheckResendApplicationMessageWithPeerExchange(nlTestSuite * inSuite, void *
     rm->ClearRetransTable(rc);
 }
 
+void CheckResendApplicationMessageWithLostAcks(nlTestSuite * inSuite, void * inContext)
+{
+    TestContext & ctx = *reinterpret_cast<TestContext *>(inContext);
+
+    ctx.GetInetLayer().SystemLayer()->Init(nullptr);
+
+    chip::System::PacketBufferHandle buffer = chip::MessagePacketBuffer::NewWithData(PAYLOAD, sizeof(PAYLOAD));
+    NL_TEST_ASSERT(inSuite, !buffer.IsNull());
+
+    CHIP_ERROR err = CHIP_NO_ERROR;
+
+    MockAppDelegate mockReceiver;
+    err = ctx.GetExchangeManager().RegisterUnsolicitedMessageHandlerForType(Echo::MsgType::EchoRequest, &mockReceiver);
+    NL_TEST_ASSERT(inSuite, err == CHIP_NO_ERROR);
+
+    mockReceiver.mTestSuite = inSuite;
+
+    MockAppDelegate mockSender;
+    ExchangeContext * exchange = ctx.NewExchangeToPeer(&mockSender);
+    NL_TEST_ASSERT(inSuite, exchange != nullptr);
+
+    ReliableMessageMgr * rm     = ctx.GetExchangeManager().GetReliableMessageMgr();
+    ReliableMessageContext * rc = exchange->GetReliableMessageContext();
+    NL_TEST_ASSERT(inSuite, rm != nullptr);
+    NL_TEST_ASSERT(inSuite, rc != nullptr);
+
+    rc->SetConfig({
+        1, // CHIP_CONFIG_RMP_DEFAULT_INITIAL_RETRY_INTERVAL
+        1, // CHIP_CONFIG_RMP_DEFAULT_ACTIVE_RETRY_INTERVAL
+    });
+
+    mockReceiver.mDropAckResponse = true;
+
+    // Let's not drop any messages. We'll drop acks for this test.
+    gLoopback.mSendMessageCount    = 0;
+    gLoopback.mNumMessagesToDrop   = 0;
+    gLoopback.mDroppedMessageCount = 0;
+
+    // Ensure the retransmit table is empty right now
+    NL_TEST_ASSERT(inSuite, rm->TestGetCountRetransTable() == 0);
+
+    err = exchange->SendMessage(Echo::MsgType::EchoRequest, std::move(buffer));
+    NL_TEST_ASSERT(inSuite, err == CHIP_NO_ERROR);
+    exchange->Close();
+
+    // Ensure the message was not dropped, and was added to retransmit table
+    NL_TEST_ASSERT(inSuite, gLoopback.mSendMessageCount == 1);
+    NL_TEST_ASSERT(inSuite, gLoopback.mDroppedMessageCount == 0);
+    NL_TEST_ASSERT(inSuite, rm->TestGetCountRetransTable() == 1);
+    NL_TEST_ASSERT(inSuite, mockReceiver.IsOnMessageReceivedCalled);
+
+    // 1 tick is 64 ms, sleep 65 ms to trigger first re-transmit
+    test_os_sleep_ms(65);
+    ReliableMessageMgr::Timeout(&ctx.GetSystemLayer(), rm, CHIP_SYSTEM_NO_ERROR);
+
+    // Ensure the retransmit message was also not dropped, and is still there in the retransmit table
+    NL_TEST_ASSERT(inSuite, gLoopback.mSendMessageCount == 2);
+    NL_TEST_ASSERT(inSuite, gLoopback.mDroppedMessageCount == 0);
+    NL_TEST_ASSERT(inSuite, rm->TestGetCountRetransTable() == 1);
+    NL_TEST_ASSERT(inSuite, mockReceiver.IsOnMessageReceivedCalled);
+
+    // Let's not drop the ack on the next retry
+    mockReceiver.mDropAckResponse = false;
+
+    // 1 tick is 64 ms, sleep 65 ms to trigger first re-transmit
+    test_os_sleep_ms(65);
+    ReliableMessageMgr::Timeout(&ctx.GetSystemLayer(), rm, CHIP_SYSTEM_NO_ERROR);
+
+    // Ensure the message was retransmitted, and is no longer in the retransmit table
+    NL_TEST_ASSERT(inSuite, gLoopback.mSendMessageCount >= 3);
+    NL_TEST_ASSERT(inSuite, gLoopback.mDroppedMessageCount == 0);
+
+    // TODO - Enable test for lost CRMP ack messages
+    // The following check is commented out because of https://github.com/project-chip/connectedhomeip/issues/7292
+    //    NL_TEST_ASSERT(inSuite, rm->TestGetCountRetransTable() == 0);
+    NL_TEST_ASSERT(inSuite, mockReceiver.IsOnMessageReceivedCalled);
+
+    mockReceiver.mTestSuite = nullptr;
+
+    err = ctx.GetExchangeManager().UnregisterUnsolicitedMessageHandlerForType(Echo::MsgType::EchoRequest);
+    NL_TEST_ASSERT(inSuite, err == CHIP_NO_ERROR);
+
+    rm->ClearRetransTable(rc);
+}
+
 void CheckResendSessionEstablishmentMessageWithPeerExchange(nlTestSuite * inSuite, void * inContext)
 {
     // Making this static to reduce stack usage, as some platforms have limits on stack size.
@@ -609,6 +698,7 @@ const nlTest sTests[] =
     NL_TEST_DEF("Test ReliableMessageMgr::CheckCloseExchangeAndResendApplicationMessage", CheckCloseExchangeAndResendApplicationMessage),
     NL_TEST_DEF("Test ReliableMessageMgr::CheckFailedMessageRetainOnSend", CheckFailedMessageRetainOnSend),
     NL_TEST_DEF("Test ReliableMessageMgr::CheckResendApplicationMessageWithPeerExchange", CheckResendApplicationMessageWithPeerExchange),
+    NL_TEST_DEF("Test ReliableMessageMgr::CheckResendApplicationMessageWithLostAcks", CheckResendApplicationMessageWithLostAcks),
     NL_TEST_DEF("Test ReliableMessageMgr::CheckResendSessionEstablishmentMessageWithPeerExchange", CheckResendSessionEstablishmentMessageWithPeerExchange),
     NL_TEST_DEF("Test ReliableMessageMgr::CheckSendStandaloneAckMessage", CheckSendStandaloneAckMessage),