diff --git a/README.md b/README.md
index 7af1fdb72..7788dafa7 100644
--- a/README.md
+++ b/README.md
@@ -97,6 +97,13 @@ tsx watch ./file.ts
 All imported files are watched except from the following directories:
 `node_modules`, `bower_components`, `vendor`, `dist`, and `.*` (hidden directories).
 
+#### Ignore files from watch
+
+To exclude files from being watched, pass in a path or glob to the `--ignore` flag:
+```sh
+tsx watch --ignore ./ignore-me.js --ignore ./ignore-me-too.js ./file.ts
+```
+
 #### Tips
 - Press <kbd>Return</kbd> to manually rerun
 - Pass in `--clear-screen=false` to disable clearing the screen on rerun
diff --git a/src/watch/index.ts b/src/watch/index.ts
index aaba93ba8..3eb2504e0 100644
--- a/src/watch/index.ts
+++ b/src/watch/index.ts
@@ -27,7 +27,11 @@ const flags = {
 		description: 'Clearing the screen on rerun',
 		default: true,
 	},
-};
+	ignore: {
+		type: [String],
+		description: 'Paths & globs to exclude from being watched',
+	},
+} as const;
 
 export const watchCommand = command({
 	name: 'watch',
@@ -47,6 +51,7 @@ export const watchCommand = command({
 		noCache: argv.flags.noCache,
 		tsconfigPath: argv.flags.tsconfig,
 		clearScreen: argv.flags.clearScreen,
+		ignore: argv.flags.ignore,
 		ipc: true,
 	};
 
@@ -123,6 +128,8 @@ export const watchCommand = command({
 
 				// Distribution files
 				'**/dist/**',
+
+				...options.ignore,
 			],
 			ignorePermissionErrors: true,
 		},
diff --git a/tests/specs/watch.ts b/tests/specs/watch.ts
index 6d83f7d39..fe2022501 100644
--- a/tests/specs/watch.ts
+++ b/tests/specs/watch.ts
@@ -1,4 +1,5 @@
 import path from 'path';
+import { setTimeout } from 'timers/promises';
 import { testSuite, expect } from 'manten';
 import { createFixture } from 'fs-fixture';
 import { tsx } from '../utils/tsx';
@@ -141,5 +142,58 @@ export default testSuite(async ({ describe }, fixturePath: string) => {
 			// 	await tsxProcess;
 			// }, 2000);
 		});
+
+		describe('ignore', ({ test }) => {
+			test('file path & glob', async () => {
+				const entryFile = 'index.js';
+				const fileA = 'file-a.js';
+				const fileB = 'directory/file-b.js';
+				let value = Date.now();
+
+				const fixture = await createFixture({
+					[entryFile]: `
+						import valueA from './${fileA}'
+						import valueB from './${fileB}'
+						console.log(valueA, valueB)
+					`.trim(),
+					[fileA]: `export default ${value}`,
+					[fileB]: `export default ${value}`,
+				});
+
+				const tsxProcess = tsx({
+					args: [
+						'watch',
+						'--clear-screen=false',
+						`--ignore=${path.join(fixture.path, fileA)}`,
+						`--ignore=${path.join(fixture.path, 'directory/*')}`,
+						path.join(fixture.path, entryFile),
+					],
+				});
+
+				tsxProcess.stdout!.on('data', async (data: Buffer) => {
+					const chunkString = data.toString();
+					if (chunkString === `${value} ${value}\n`) {
+						value = Date.now();
+						await Promise.all([
+							fixture.writeFile(fileA, `export default ${value}`),
+							fixture.writeFile(fileB, `export default ${value}`),
+						]);
+
+						await setTimeout(500);
+						await fixture.writeFile(entryFile, 'console.log("TERMINATE")');
+					}
+
+					if (chunkString === 'TERMINATE\n') {
+						tsxProcess.kill();
+					}
+				});
+
+				const tsxProcessResolved = await tsxProcess;
+				await fixture.rm();
+
+				expect(tsxProcessResolved.stdout).not.toMatch(`${value} ${value}`);
+				expect(tsxProcessResolved.stderr).toBe('');
+			}, 5000);
+		});
 	});
 });