diff --git a/modules/prebidServerBidAdapter/index.js b/modules/prebidServerBidAdapter/index.js
index 9371083c8d2..abad0284e9e 100644
--- a/modules/prebidServerBidAdapter/index.js
+++ b/modules/prebidServerBidAdapter/index.js
@@ -120,7 +120,7 @@ export function resetSyncedStatus() {
 /**
  * @param  {Array} bidderCodes list of bidders to request user syncs for.
  */
-function queueSync(bidderCodes, gdprConsent) {
+function queueSync(bidderCodes, gdprConsent, uspConsent) {
   if (_synced) {
     return;
   }
@@ -147,6 +147,12 @@ function queueSync(bidderCodes, gdprConsent) {
       payload.gdpr_consent = gdprConsent.consentString;
     }
   }
+
+  // US Privace (CCPA) support
+  if (uspConsent) {
+    payload.us_privacy = uspConsent;
+  }
+
   const jsonPayload = JSON.stringify(payload);
   ajax(_s2sConfig.syncEndpoint,
     (response) => {
@@ -766,24 +772,21 @@ const OPEN_RTB_PROTOCOL = {
       }
     }
 
-    if (bidRequests && bidRequests[0].gdprConsent) {
-      // note - gdprApplies & consentString may be undefined in certain use-cases for consentManagement module
-      let gdprApplies;
-      if (typeof bidRequests[0].gdprConsent.gdprApplies === 'boolean') {
-        gdprApplies = bidRequests[0].gdprConsent.gdprApplies ? 1 : 0;
-      }
-
-      if (request.regs) {
-        if (request.regs.ext) {
-          request.regs.ext.gdpr = gdprApplies;
-        } else {
-          request.regs.ext = { gdpr: gdprApplies };
+    if (bidRequests) {
+      if (bidRequests[0].gdprConsent) {
+        // note - gdprApplies & consentString may be undefined in certain use-cases for consentManagement module
+        let gdprApplies;
+        if (typeof bidRequests[0].gdprConsent.gdprApplies === 'boolean') {
+          gdprApplies = bidRequests[0].gdprConsent.gdprApplies ? 1 : 0;
         }
-      } else {
-        request.regs = { ext: { gdpr: gdprApplies } };
+        utils.deepSetValue(request, 'regs.ext.gdpr', gdprApplies);
+        utils.deepSetValue(request, 'user.ext.consent', bidRequests[0].gdprConsent.consentString);
       }
 
-      utils.deepSetValue(request, 'user.ext.consent', bidRequests[0].gdprConsent.consentString);
+      // US Privacy (CCPA) support
+      if (bidRequests[0].uspConsent) {
+        utils.deepSetValue(request, 'regs.ext.us_privacy', bidRequests[0].uspConsent);
+      }
     }
 
     if (getConfig('coppa') === true) {
@@ -984,12 +987,17 @@ export function PrebidServer() {
       .filter(utils.uniques);
 
     if (_s2sConfig && _s2sConfig.syncEndpoint) {
-      let consent = (Array.isArray(bidRequests) && bidRequests.length > 0) ? bidRequests[0].gdprConsent : undefined;
+      let gdprConsent, uspConsent;
+      if (Array.isArray(bidRequests) && bidRequests.length > 0) {
+        gdprConsent = bidRequests[0].gdprConsent;
+        uspConsent = bidRequests[0].uspConsent;
+      }
+
       let syncBidders = _s2sConfig.bidders
         .map(bidder => adapterManager.aliasRegistry[bidder] || bidder)
         .filter((bidder, index, array) => (array.indexOf(bidder) === index));
 
-      queueSync(syncBidders, consent);
+      queueSync(syncBidders, gdprConsent, uspConsent);
     }
 
     const request = protocolAdapter().buildRequest(s2sBidRequest, bidRequests, validAdUnits);
diff --git a/src/adapters/bidderFactory.js b/src/adapters/bidderFactory.js
index 7ace0f786e7..18408e78d17 100644
--- a/src/adapters/bidderFactory.js
+++ b/src/adapters/bidderFactory.js
@@ -187,7 +187,7 @@ export function newBidder(spec) {
       function afterAllResponses() {
         done();
         events.emit(CONSTANTS.EVENTS.BIDDER_DONE, bidderRequest);
-        registerSyncs(responses, bidderRequest.gdprConsent);
+        registerSyncs(responses, bidderRequest.gdprConsent, bidderRequest.uspConsent);
       }
 
       const validBidRequests = bidderRequest.bids.filter(filterAndWarn);
@@ -330,13 +330,13 @@ export function newBidder(spec) {
     }
   });
 
-  function registerSyncs(responses, gdprConsent) {
+  function registerSyncs(responses, gdprConsent, uspConsent) {
     if (spec.getUserSyncs) {
       let filterConfig = config.getConfig('userSync.filterSettings');
       let syncs = spec.getUserSyncs({
         iframeEnabled: !!(config.getConfig('userSync.iframeEnabled') || (filterConfig && (filterConfig.iframe || filterConfig.all))),
         pixelEnabled: !!(config.getConfig('userSync.pixelEnabled') || (filterConfig && (filterConfig.image || filterConfig.all))),
-      }, responses, gdprConsent);
+      }, responses, gdprConsent, uspConsent);
       if (syncs) {
         if (!Array.isArray(syncs)) {
           syncs = [syncs];
diff --git a/test/spec/modules/prebidServerBidAdapter_spec.js b/test/spec/modules/prebidServerBidAdapter_spec.js
index 5ee05ad401e..cdb674509cb 100644
--- a/test/spec/modules/prebidServerBidAdapter_spec.js
+++ b/test/spec/modules/prebidServerBidAdapter_spec.js
@@ -702,6 +702,109 @@ describe('S2S Adapter', function () {
       });
     });
 
+    describe('us_privacy (ccpa) consent data', function () {
+      afterEach(function () {
+        config.resetConfig();
+        $$PREBID_GLOBAL$$.requestBids.removeAll();
+      });
+
+      it('is added to ortb2 request when in bidRequest', function () {
+        let ortb2Config = utils.deepClone(CONFIG);
+        ortb2Config.endpoint = 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        config.setConfig({ s2sConfig: ortb2Config });
+
+        let uspBidRequest = utils.deepClone(BID_REQUESTS);
+        uspBidRequest[0].uspConsent = '1NYN';
+
+        adapter.callBids(REQUEST, uspBidRequest, addBidResponse, done, ajax);
+        let requestBid = JSON.parse(requests[0].requestBody);
+
+        expect(requestBid.regs.ext.us_privacy).is.equal('1NYN');
+
+        config.resetConfig();
+        config.setConfig({ s2sConfig: CONFIG });
+
+        adapter.callBids(REQUEST, BID_REQUESTS, addBidResponse, done, ajax);
+        requestBid = JSON.parse(requests[1].requestBody);
+
+        expect(requestBid.regs).to.not.exist;
+      });
+
+      it('is added to cookie_sync request when in bidRequest', function () {
+        let cookieSyncConfig = utils.deepClone(CONFIG);
+        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        config.setConfig({ s2sConfig: cookieSyncConfig });
+
+        let uspBidRequest = utils.deepClone(BID_REQUESTS);
+        uspBidRequest[0].uspConsent = '1YNN';
+
+        adapter.callBids(REQUEST, uspBidRequest, addBidResponse, done, ajax);
+        let requestBid = JSON.parse(requests[0].requestBody);
+
+        expect(requestBid.us_privacy).is.equal('1YNN');
+        expect(requestBid.bidders).to.contain('appnexus').and.to.have.lengthOf(1);
+        expect(requestBid.account).is.equal('1');
+      });
+    });
+
+    describe('gdpr and us_privacy (ccpa) consent data', function () {
+      afterEach(function () {
+        config.resetConfig();
+        $$PREBID_GLOBAL$$.requestBids.removeAll();
+      });
+
+      it('is added to ortb2 request when in bidRequest', function () {
+        let ortb2Config = utils.deepClone(CONFIG);
+        ortb2Config.endpoint = 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        config.setConfig({ s2sConfig: ortb2Config });
+
+        let consentBidRequest = utils.deepClone(BID_REQUESTS);
+        consentBidRequest[0].uspConsent = '1NYN';
+        consentBidRequest[0].gdprConsent = {
+          consentString: 'abc123',
+          gdprApplies: true
+        };
+
+        adapter.callBids(REQUEST, consentBidRequest, addBidResponse, done, ajax);
+        let requestBid = JSON.parse(requests[0].requestBody);
+
+        expect(requestBid.regs.ext.us_privacy).is.equal('1NYN');
+        expect(requestBid.regs.ext.gdpr).is.equal(1);
+        expect(requestBid.user.ext.consent).is.equal('abc123');
+
+        config.resetConfig();
+        config.setConfig({ s2sConfig: CONFIG });
+
+        adapter.callBids(REQUEST, BID_REQUESTS, addBidResponse, done, ajax);
+        requestBid = JSON.parse(requests[1].requestBody);
+
+        expect(requestBid.regs).to.not.exist;
+        expect(requestBid.user).to.not.exist;
+      });
+
+      it('is added to cookie_sync request when in bidRequest', function () {
+        let cookieSyncConfig = utils.deepClone(CONFIG);
+        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        config.setConfig({ s2sConfig: cookieSyncConfig });
+
+        let consentBidRequest = utils.deepClone(BID_REQUESTS);
+        consentBidRequest[0].uspConsent = '1YNN';
+        consentBidRequest[0].gdprConsent = {
+          consentString: 'abc123def',
+          gdprApplies: true
+        };
+
+        adapter.callBids(REQUEST, consentBidRequest, addBidResponse, done, ajax);
+        let requestBid = JSON.parse(requests[0].requestBody);
+
+        expect(requestBid.us_privacy).is.equal('1YNN');
+        expect(requestBid.gdpr).is.equal(1);
+        expect(requestBid.gdpr_consent).is.equal('abc123def');
+        expect(requestBid.bidders).to.contain('appnexus').and.to.have.lengthOf(1);
+        expect(requestBid.account).is.equal('1');
+      });
+    });
+
     it('sets invalid cacheMarkup value to 0', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
         cacheMarkup: 999