diff --git a/dbms/src/Storages/Transaction/KVStore.cpp b/dbms/src/Storages/Transaction/KVStore.cpp
index 4fe68e6086e..fb21be2d2b7 100644
--- a/dbms/src/Storages/Transaction/KVStore.cpp
+++ b/dbms/src/Storages/Transaction/KVStore.cpp
@@ -709,11 +709,17 @@ void WaitCheckRegionReady(
                 const auto & region_error = resp.region_error();
                 if (region_error.has_region_not_found() || region_error.has_epoch_not_match())
                     need_retry = false;
+                LOG_DEBUG(log,
+                          "neglect error region {} not found {} epoch not match {}",
+                          region_id,
+                          region_error.has_region_not_found(),
+                          region_error.has_epoch_not_match());
             }
             if (!need_retry)
             {
+                // `read_index` can be zero if region error happens.
+                // It is not worthy waiting applying and reading index again.
                 // if region is able to get latest commit-index from TiKV, we should make it available only after it has caught up.
-                assert(resp.read_index() != 0);
                 regions_to_check.emplace(region_id, resp.read_index());
                 remain_regions.erase(region_id);
             }